Comedy for a Cure

Comedy for a Cure Comedy for a Cure® is the Tuberous Sclerosis Alliance's signature fundraising event, held annually in Hollywood, CA.

Proceeds support our efforts to fund tuberous sclerosis complex (TSC) research and support programs for anyone affected by the disorder.

Dr. Raj Rajaraman receives accolade for tuberous sclerosis complex care at UCLA Mattel Children’s Hospital!Learn more:ht...
05/18/2026

Dr. Raj Rajaraman receives accolade for tuberous sclerosis complex care at UCLA Mattel Children’s Hospital!

Learn more:https://hubs.li/Q04gZpSn0

Dr. Rajsekar Rajaraman, assistant professor of pediatric neurology at the UCLA Mattel Children’s Hospital and clinic director of the UCLA Tuberous Sclerosis Complex (TSC) Center of Excellence, was awarded the TSC Champion award by the TSC Alliance for his outstanding care for patients with tuberou...

Oh what a night! 🎶Last night, we celebrated the 25th Anniversary of Comedy for a Cure, and what an unforgettable evening...
04/20/2026

Oh what a night! 🎶
Last night, we celebrated the 25th Anniversary of Comedy for a Cure, and what an unforgettable evening it was. From incredible comedy acts and magical performances to a one-of-a-kind signed Simpsons artwork, the night was filled with unforgettable moments.

Thanks to you, we raised an amazing $329,000!!

Thank you to the amazing comedian committee, planning committee, talent, honorees, and sponsors who made this milestone celebration possible.
Take a moment to scroll through some of the highlights from this truly special night.

A special thanks again to our sponsors:
Headliner sponsor: Opennode
Standing Ovation sponsor: Jazz Pharmaceuticals
Bravo sponsors: Jim and Andrea Maginn Memorial Trust, Cathy and David Krinsky, Seraphina Holmes Charitable Fund, Upsher Smith
Cheers sponsors: UCLA, Anita Bhatia Foundation for Tomorrow, Diane McSwain, Gondolabio, Lundbeck, Massmutual SpecialCare, Szilagyi/Graff Family, UCB
Encore sponsors: Nobelpharma, Ray Chan, Tim and Kathy Dills
Patron Plus sponsors: Hyman Family, Knobbe Martens
Patron Sponsors: Kristen and Mark Perlmutter, Keith Hall Family, Ted and Peggy Mastroianni, Dr. Mark Hyman, Christy Hobart and Henry Shapiro

Today marks 25 years of Comedy for a Cure — 25 years of comedy, compassion, and community 💫25 years of laughter, love, a...
04/19/2026

Today marks 25 years of Comedy for a Cure — 25 years of comedy, compassion, and community 💫

25 years of laughter, love, and life-changing support for the TSC community—and tonight we celebrate it all together!

We can’t wait to see you at the Irvine Improv for this special silver anniversary show.

Snag your last-minute tickets at the door—you won’t want to miss this one-of-a-kind celebration.

1️⃣ day until the 25th Annual Comedy for a Cure! Join us tomorrow, April 19 at 4 pm CT at Irvine Improv.Show only ticket...
04/18/2026

1️⃣ day until the 25th Annual Comedy for a Cure! Join us tomorrow, April 19 at 4 pm CT at Irvine Improv.

Show only tickets available at https://hubs.li/Q04cD9tZ0 and at the door.

See you there!

🎤 Wendy Liebman is hitting the stage at Comedy for a Cure!Join Wendy and a lineup of incredible comedians on April 19 at...
04/13/2026

🎤 Wendy Liebman is hitting the stage at Comedy for a Cure!

Join Wendy and a lineup of incredible comedians on April 19 at the Irvine Improv for a night of laughs supporting the TSC Alliance.

🎟️ Tickets are still available—get yours now at https://hubs.li/Q04bLgFm0

🎤✨ Comedy royalty is coming to town! ✨🎤With her razor‑sharp wit, impeccable timing, and iconic charm, Rita Rudner has be...
04/09/2026

🎤✨ Comedy royalty is coming to town! ✨🎤
With her razor‑sharp wit, impeccable timing, and iconic charm, Rita Rudner has been making audiences laugh for decades—from sold‑out Vegas shows to countless TV appearances.

Now, the legendary comedian takes the stage for the 25th Annual Comedy for a Cure, on April 19 at Irvine Improv bringing big laughs in support of the TSC Community.💙

🎟️ Don’t miss it: https://hubs.li/Q04bhF1y0

Laugh for a great cause at the 25th Annual Comedy for a Cure on April 19 at Irvine Improv!Featuring an all‑star lineup:⭐...
03/31/2026

Laugh for a great cause at the 25th Annual Comedy for a Cure on April 19 at Irvine Improv!

Featuring an all‑star lineup:
⭐ Rita Rudner
⭐ Jim O’Heir
⭐ Craig Shoemaker
⭐ Mo Collins
⭐ Wendy Liebman
⭐ Priya Mehta

🎟️ 100% of proceeds benefit the TSC Alliance.

👉 Get your tickets now: https://hubs.li/Q0497PY20

03/23/2026
Last chance to purchase early bird tickets!Join us for the 25th Annual Comedy for a Cure benefiting the TSC Alliance on ...
03/21/2026

Last chance to purchase early bird tickets!

Join us for the 25th Annual Comedy for a Cure benefiting the TSC Alliance on Sunday, April 19, 2026 at the Irvine Improv.

During the event we will be honoring Anna Todd with the TSC Spotlight Award.

Anna Todd is a​​​​​​​ TSC mom with a 14-year-old son, Asher, who was diagnosed as an infant. Her entrance into the world of TSC was dramatic when her son started having seizures days after he was b​​​​​​​orn. As a young mom she had to not only adjust to caring for an infant but also had to learn how to navigate the challenges of a rare disease. Anna began writing as an outlet and found her voice in this medium. She became a best-selling, world renown author of romance novels with publications in multiple languages.​​​​​​​ Anna has most recently used this platform to write a new book, The Last Sunrise, which follows the story of a young adult with TSC and will be released as a feature film in the Summer of 2026!

Buy your tickets today and celebrate the TSC community and our amazing honorees: https://hubs.li/Q047Qcnq0

TSC Alliance® to Host 24th Annual Comedy for a Cure® on April 6 in Los Angeles!Learn more:
03/11/2025

TSC Alliance® to Host 24th Annual Comedy for a Cure® on April 6 in Los Angeles!

Learn more:

/PRNewswire/ -- Today, the TSC Alliance® announced its 24th Annual Comedy for a Cure® will be held Sunday, April 6, once again at the historic Vibiana in Los...

Address

527 Spectrum Center Drive
Irvine, CA
92618

Alerts

Be the first to know and let us send you an email when Comedy for a Cure posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Organization

Send a message to Comedy for a Cure:

Share