The Alpers Awareness Foundation

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The Alpers Awareness Foundation https://www.alpersawareness.org

For those who carry the POLG mutation. Please consult your physician!!!Nicotinamide riboside reduces glial inflammation ...
06/29/2026

For those who carry the POLG mutation. Please consult your physician!!!

Nicotinamide riboside reduces glial inflammation and boosts mitochondrial function

Astrocyte dysfunction plays a pivotal role in the pathogenesis of POLG-related mitochondrial diseases, yet the underlying mechanisms remain poorly understood. Here, we employed human iPSC-derived astrocytes, cortical organoids and astrocyte-neuron ...

06/22/2026

Effectiveness of antiseizure meds on mitochondrial and metabolic illnesses, including Alpers.

Antiseizure Medications Impact Mitochondrial Ion Channels via Novel Bioenergetic and Neural Mechanisms

01/29/2026

Another potential systemic treatment for Alpers.

Mitochondrial Transplantation as a Therapeutic Strategy for
Inherited Mitochondrial Diseases

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