OPO Startups

OPO Startups OPO Startups is a place where entrepreneurs can connect, work and collaborate. OPO is a co-working center for digital Startups.

Located in the newly renovated “Old Post Office” building, the 10,000 square foot facility provides regional startups with affordable workspace and access to mentors, potential investors, programming, educational resources and a community of local entrepreneurs.

04/29/2026

Our next Tech Talk is Wednesday, May 13th with Gary Kellmann, CEO and Managing Partner of zPods. He will lead a discussion on OpenClaw, an AI platform for building and automating real-world workflows. The event is free and all experience levels welcome!

Date: Wednesday, May 13th
Time: 5:00 - 7:00 pm
Location: OPO Startups (119 S Main St)
RSVP: www.confluencetechhub.com/techtalks

Join us next week for a Tech Talk on how to integrate AI into your business!
04/15/2026

Join us next week for a Tech Talk on how to integrate AI into your business!

Meet your speaker for the upcoming Tech Talk!

Jim Gera, CEO & Co-Founder of Harmonic Health, has spent the last few years doing what most businesses are still trying to figure out: actually integrating AI into everyday operations.

On April 22, he’s bringing that experience to OPO Startups in Saint Charles for a Tech Talk. He’ll share what worked, what didn’t, and how to get your team to truly adopt AI tools.

Free to attend. RSVP here:
https://confluencetechhub.com/techtalks

01/07/2026

We are thrilled to announce Randy Schilling of OPO Startups as one of the newest members of our Board of Directors.

Randy is a long-time supporter of the EDC and is a local champion for small businesses, entrepreneurs, and STEM education. In 2021, he launched the Randy Schilling STEM Educators Grant with the EDC. In 2024, he furthered that commitment by announcing a 10-year, $100,000 endowment to fund the program.

Welcome, Randy!

11/23/2025
Exciting news! The finalists for this year’s Demo Day were just announced!These startups are doing incredible things in ...
11/05/2025

Exciting news! The finalists for this year’s Demo Day were just announced!

These startups are doing incredible things in AI and tech, and we can’t wait to see them pitch live at OPO Startups.

Join us for Demo Day! RSVP here:
👉 confluencetechhub.com/demodayevent

10/22/2025

*LAST CALL!* All Demo Day applications are due by midnight tonight!

Don’t miss your chance to pitch your startup for a chance to win cash, and put your startup on the map in St. Charles County.

Apply now: www.confluencetechhub.com/demodayapplication

What an incredible night on Historic Main Street! Supper Club 2025 brought the community together for amazing food, loca...
09/05/2025

What an incredible night on Historic Main Street! Supper Club 2025 brought the community together for amazing food, local partnerships, and an unforgettable celebration. Huge thanks to St. Charles Main Street Foundation for putting on such a special event that continues to make our Main Street shine. We’re already looking forward to next year!

Let's help support our local Main Street with their raffle fundraiser! St. Charles Main Street Foundation is hosting a r...
08/26/2025

Let's help support our local Main Street with their raffle fundraiser! St. Charles Main Street Foundation is hosting a raffle full of one of a kind baskets and experiences from right here on Main Street. Get your tickets! https://stcmain.org/raffle

08/25/2025

Reminder: Tomorrow’s Tech Talk is one you won’t want to miss!

Join us Tuesday at 5 PM at OPO Startups for a Tech Talk with Ryan O’Neil, Founder & CEO of Curate. He’ll show how AI can streamline sales workflows, boost conversions, and free your team to focus on what matters.

Whether you're in sales, marketing, or tech, this one's for you!

RSVP Now: https://confluencetechhub.com/techtalks

2025 Demo Day Applications are now open!
08/21/2025

2025 Demo Day Applications are now open!

The 2025 Demo Day applications are now open!

Think you’ve got the next big idea? Apply to pitch at Demo Day and compete for cash, exposure, and connections. Applications close October 22.

More details: www.confluencetechhub.com/demodayapplication

Address

119 S Main Street
St. Charles, MO
63301

Opening Hours

Monday 8am - 4pm
Tuesday 8am - 4pm
Wednesday 8am - 4pm
Thursday 8am - 4pm

Telephone

(314) 328-4656

Alerts

Be the first to know and let us send you an email when OPO Startups posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Organization

Send a message to OPO Startups:

Share