Colorectal Cancer Alliance

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Colorectal Cancer Alliance Working with our nation of passionate allies, we exist to end colorectal cancer within our lifetime. Newly diagnosed or need support?
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Call us at (877) 422-2030 or visit colorectalcancer.org.

The FDA has approved Tecentriq with chemotherapy after surgery for some people with stage III colon cancer whose tumors ...
10/14/2026

The FDA has approved Tecentriq with chemotherapy after surgery for some people with stage III colon cancer whose tumors test dMMR.

In the ATOMIC trial, 86% of people who received Tecentriq plus chemotherapy were living without their cancer returning at three years, compared with 76% who received chemotherapy alone.

Ask your care team whether your tumor was tested for dMMR and whether this treatment could be an option for you. The Alliance’s free Helpline is here to help: (877) 422-2030.

Read more on our blog 👉 https://crcancer.org/Blog-Tecentriq

In a new Georgetown University feature, Dr. John Marshall, the Alliance’s chief medical consultant, reflects on the rise...
10/13/2026

In a new Georgetown University feature, Dr. John Marshall, the Alliance’s chief medical consultant, reflects on the rise of young-onset colorectal cancer and the urgent need to better understand its causes, accelerate clinical trials, and develop more precise treatments.

Through initiatives like KLEOS, Dr. Marshall and the Alliance are working to move promising treatments forward faster, because patients cannot afford to wait.

Read more 👉 https://bit.ly/Georgetown-KLEOS

"In February 2024, at 44 years old, I experienced severe stomach pain that led me to the emergency room. I was told my c...
10/11/2026

"In February 2024, at 44 years old, I experienced severe stomach pain that led me to the emergency room. I was told my colon was swollen and to follow up with my GI doctor. A month later, a colonoscopy changed my life: I was diagnosed with Stage IIIB colon cancer. Two weeks later, I underwent surgery to remove the mass.

I began chemotherapy in May 2024 and completed treatment in July, ringing the bell surrounded by family and friends. I celebrated by traveling to Greece and Italy, believing I was finally moving forward. Three months later, scans showed that the cancer had spread to my liver.

I continued chemotherapy through December 2024 and underwent liver surgery in January 2025. After months of good scans, new testing in August 2025 revealed another occurrence in my liver and a nodule in my lung. I faced more chemotherapy, lung surgery, radiation, and liver ablation. By April 2026, those areas had been treated.

Now, in September 2026, I am facing chemotherapy again. There is a nodule in my left lung and two lesions in my liver. Yet through every diagnosis, surgery, treatment, setback, and loss, I have persevered.

My husband has walked beside me through every chapter—surgeries, chemotherapy, uncertainty, tears, and difficult news. My mother was also one of my greatest sources of strength. She passed away in May 2026, shortly after my liver ablation. I miss her deeply, but I carry the strength and lessons she gave me.

Cancer has taught me to protect my peace, appreciate every day, and remember that a diagnosis does not define my story.

Through it all, my faith has carried me when I could not carry myself. My story is still being written, and as long as I have breath, I will continue to stand, move forward, and encourage others." - Ramona M.

Support the future of colorectal cancer research — visit https://crcancer.org/Cure-26-FB

Colorectal cancer affects more than physical health. Patients, survivors, and caregivers may experience fear, anxiety, g...
10/10/2026

Colorectal cancer affects more than physical health. Patients, survivors, and caregivers may experience fear, anxiety, grief, isolation, and emotional exhaustion. No one should have to navigate those feelings alone.

On World Mental Health Day, we’re reminding you that asking for support is a sign of strength. Save the Alliance’s Helpline number and call 877-422-2030, Monday through Friday, 9 a.m.–5 p.m. ET, to connect with a member of our Cancer Care Team.

You don’t have to do this alone.

Thank you to Foundation Medicine for their support of our Cancer Care program.

"When anyone with a philanthropic streak seeks my advice, I ask them one question: 'Do you have a donor-advised fund?' I...
10/08/2026

"When anyone with a philanthropic streak seeks my advice, I ask them one question: 'Do you have a donor-advised fund?' I only ever hear two answers. 'Yes, and I love it.' Or, 'What's that?'

A donor-advised fund, or DAF, makes giving easy, efficient, and effective. You contribute cash or stock, get the tax benefits, and support causes you care about, right from your phone. As chair of Fidelity Charitable, I can tell you it's a great way to give, both for you and for the charities.

On this DAF Day, I'm asking you to support a charity that's close to my heart — the Colorectal Cancer Alliance.

A year ago, my routine colonoscopy found stage III colorectal cancer. And just months before that, my son-in-law was diagnosed at the same stage. He's doing well now, but I'm 65 and he's 36. That's not OK. This disease is striking younger people, and we have to find out how to stop it.

We were lucky to get excellent care, fast. Not everyone is.

When I looked at the impact the Colorectal Cancer Alliance makes for every dollar raised, I thought it was impossible. Its research, patient support, and prevention programs are why I joined its Board of Directors. If you care about cancer, there's no better place to give. It's not even close.

So start a DAF today, or recommend a grant from the one you have. Either way, imagine what the Alliance could do with even more support." - Lenny M.

Learn more about Donor Advised Funds (DAF) 👉 https://crcancer.org/DAF

Biomarkers matter, and here’s why. Biomarkers are biological clues like DNA, proteins, or genetic mutations that can be ...
10/07/2026

Biomarkers matter, and here’s why. Biomarkers are biological clues like DNA, proteins, or genetic mutations that can be measured in your blood or tumor tissue. They help doctors understand what makes your cancer unique and guide decisions about the best treatments for your situation.

How are they tested? Biomarker testing is done through a tissue biopsy (taking a sample from the tumor) or a liquid biopsy (a blood draw). These samples go to a lab and are analyzed for specific changes that your care team can use to personalize your treatment.

Why it’s so important? Knowing your biomarker profile can help doctors:
• Choose treatments most likely to work for you
• Avoid treatments that may not be effective
• Determine if targeted therapies or clinical trials are options
• Understand how your cancer might behave over time

Read more about the NRAS Biomarker: https://crcancer.org/NRAS-Biomarker
Read more about the KRAS Biomarker: https://crcancer.org/KRAS-Biomarker

Thank you to Amgen for supporting the development of this content.

"I got screened because I turned 45 this year, as it was highly recommended. My husband completed his screening two year...
10/06/2026

"I got screened because I turned 45 this year, as it was highly recommended. My husband completed his screening two years ago, so seeing him go through it made me more comfortable scheduling mine.

While preparing, I searched for firsthand colonoscopy experiences—so I’m glad this page exists! Working from home on my clear-liquid day helped, and I drank the prescription prep very cold, over ice, while watching TV. My husband handled the kids while I “went away” to prep. LOL.

I felt full and a little nauseated at first, but once the prep started working, I felt better. A nurse suggested applying Vaseline beforehand, and I also used Preparation H wipes. Both helped me avoid pain or burning.

My prep was split into two parts, so I woke up at 2:30 a.m. for the second round. By 8 a.m., I was headed to my colonoscopy. I was tired and crabby, but otherwise felt fine. The staff provided so much comfort and care.

The procedure felt like it was over in seconds. When I woke up, I had apple juice and crackers—my first food in more than a day—and learned that everything looked great!

I highly recommend getting screened. If possible, take two days off: one for prep and one for the procedure and recovery. Take care of yourself and give yourself the time. I don’t have to go back for 10 years, and I’m pretty happy about that!" - Monica

If you're 45 or older, have a family history of colorectal cancer, or are experiencing any symptoms, talk to your doctor about getting screened. Learn more and take a short screening quiz to receive personalized screening options based on your individual risk factors by visiting getscreened.org.

Seattle showed up in a big way! Together, our walkers, volunteers, fundraisers, and supporters raised more than $100K. T...
10/05/2026

Seattle showed up in a big way! Together, our walkers, volunteers, fundraisers, and supporters raised more than $100K. Thank you for every step taken and every dollar raised in support of the Alliance’s mission! 🚶‍♀️

Learn more about the Walk to End Colon Cancer and find one near you by visiting https://bit.ly/2026WECC.

We’re grateful to our generous sponsors, Topazfit, Optum, Virginia Mason Franciscan Health, and Fred Hutch, for making this day possible.

And a special thank-you to Jean-Marcus Strole Photography for beautifully capturing the day 📸

We’re so excited to partner with the Colorectal Cancer Alliance for the second year of our With Heart program. This one ...
10/05/2026

We’re so excited to partner with the Colorectal Cancer Alliance for the second year of our With Heart program. This one means a lot to us.
When we first learned through our friend Craig Melvin just how many people are diagnosed with colorectal cancer every year, we were honestly blown away. This is a cancer that touches far too many families — nearly 159,000 people are expected to be diagnosed in the U.S. this year alone. And when something affects that many people, you start thinking about the small ways you can show up. And we obviously show up with flowers.
So with every Alliance With Heart bouquet you send, a portion gives back to help fund research, screening, and support for people and families affected by colorectal cancer. It’s a really important cause, one we’re proud to stand behind again and, honestly, just one more really good reason to send someone flowers.

October 3rd is Ostomy Awareness Day! Did you know that around 1 million people in the United States live with an ostomy?...
10/03/2026

October 3rd is Ostomy Awareness Day! Did you know that around 1 million people in the United States live with an ostomy?

About 1 in every 500 Americans received a life-saving ostomy surgery, and approximately 100,000 ostomy surgeries are performed each year.

Ostomies save lives — let’s normalize them! Learn more about ostomies at https://crcancer.org/ostomy

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