The Alliance for Longevity Initiatives

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The Alliance for Longevity Initiatives is a 501(c)(4) nonprofit organization focused on advancing legislation, policies and initiatives to increase healthy human lifespan.

08/26/2026

This week, we are highlighting two conversations from the 2026 H-SPAN Summit D.C. that explored the intersection of neuroscience, aging, and longevity research, featuring leaders from Georgetown University Medical Center.

🧠 Carlo Tornatore, Georgetown University

Dr. Carlo Tornatore explores cognitive reserve, how it develops throughout our lives, and why even modest delays in the onset of dementia could have significant implications for individuals, families, and society.

🎥 Watch: https://www.youtube.com/watch?v=KtiRv4ifyDA

🧬 Bridging Neuroscience & Longevity Research

Moderator: Moshe Levi
Panelists: Bill Rebeck, Mark Burns, Carlo Tornatore

Neuroscience and geroscience have often developed along separate paths. This conversation explores where those fields intersect, including shared mechanisms of aging and neurodegeneration, what aging biology may offer Alzheimer's research, and what the longevity field can learn from neuroscience about resilience.

🎥 Watch: https://www.youtube.com/watch?v=mc4jCzgqBGM

We are especially grateful to our partners at Georgetown University Medical Center, who graciously hosted this year's H-SPAN Summit D.C. The Summit would not have been possible without their support, collaboration, and commitment to advancing conversations at the intersection of aging, health, and biomedical research.

These are just two of the many conversations from this year's Summit.

A4LI Members receive early access to the full 2026 H-SPAN Summit video catalog before each session is released publicly, along with exclusive updates, content, and opportunities to help shape the future of longevity policy.

Become a member today: https://a4li.org/become-a-member

08/24/2026

What could medicine look like if we could treat the biology of aging itself?

Twenty teams are now working to help answer that question.

XPRIZE has announced its Healthspan finalists, advancing teams developing a wide range of approaches aimed at improving healthy aging. Ten finalist teams will receive $1 million each to accelerate their work toward clinical testing.

You can check out the finalists here: https://www.xprize.org/competitions/healthspan

At A4LI, we are thrilled to see so many different scientific approaches being explored at once. There is still so much we don’t know about aging, but moments like this show just how much is changing.

The future of healthy aging is being built right now.

08/23/2026

We are excited to announce that A4LI Founder & CEO Dylan V. Livingston will be at DC Deep Tech Week: Health & Humanity on September 9 at the National Landing Experience Center in Arlington, VA.

Dylan will join an exceptional group of leaders working at the intersection of health, longevity, AI, biotechnology, and human health, including Lynda Chin, Athena Aktipis, Rudy Yoo, and Joe Betts-LaCroix.

Learn more and register here: https://luma.com/st4o2gi5

08/21/2026

Hearing loss is often treated as a normal nuisance of getting older. But research suggests it may matter more than we think.

In observational studies, hearing loss is linked to accelerated cognitive decline and a substantially higher risk of dementia. The strongest test so far came from the ACHIEVE trial, the largest randomized study of hearing treatment and cognition, published in The Lancet. Across all participants, hearing aids did not significantly slow cognitive decline, but among older adults already at higher risk of decline, treatment cut the rate of decline by about 48% over three years.

You can learn more here: https://aaic.alz.org/releases_2023/hearing-aids-slow-cognitive-decline.asp

At A4LI, we believe that protecting the senses that keep us connected and engaged is an important part of advancing healthy longevity. As the evidence linking hearing and brain health grows, it raises an important question about how we approach prevention and early detection.

With hearing loss so common and so often untreated, do you think routine hearing checks should be a standard part of protecting brain health as we age? Why or why not? Let us know in the comments below ⬇️

08/20/2026

Two new panels from the 2026 H-SPAN Summit D.C. are now live!

From translating geroscience into approved therapies to applying precision approaches to health and performance, these conversations explored some of the key questions facing the longevity field today.

🧬 Translating Geroscience from Lab to Patients

Moderated by Hanadie Yousef, with Stephen Kritchevsky, David Gobel, and Matt Kaeberlein.

The panel examines lessons from clinical efforts including the TAME trial, approaches to designing trials that can meet FDA requirements, and the scientific, regulatory, and financial challenges involved in getting the field's first interventions across the finish line.

🎥 Watch: https://www.youtube.com/watch?v=uzG7Jwxf9v0

🏃 Precision Longevity Medicine for Health & Performance

Moderated by Alina Rui Su, with Roschon Johnson, Jeffrey Gladden, and Matt Kaeberlein.

This panel explores the intersection of clinical medicine, diagnostics, and human performance, including how biomarker data is being used to inform individual decisions and where the evidence is strong, where it remains limited, and how to distinguish durable approaches from good marketing.

🎥 Watch: https://www.youtube.com/watch?v=ADEphmkGCys

These are just two of the many conversations from this year's H-SPAN Summit D.C.

A4LI Members receive early access to the full 2026 H-SPAN Summit video catalog before each session is released publicly, along with exclusive updates, content, and opportunities to help shape the future of longevity policy.

Become a member today: https://a4li.org/become-a-member

08/19/2026

For years, critics have labeled Capitol Hill a "gerontocracy." The AP News Congressional Retirements Tracker shows a massive wave of lawmakers heading for the exits this election cycle, while underscoring a broader trend: Congress has steadily aged over the last century. While dozens of members are not seeking reelection to their current seats, many aren't stepping away from public life entirely, opting instead to pursue governorships or Senate seats. As a new generation of leaders steps up, we’ll be watching to see how the demographic landscape of Congress evolves.

Nonetheless, the timing and opportunity for aging biology and longevity biotechnology have never been more ripe. At A4LI, we continue to champion this vision by advocating for policies that accelerate next-generation disease-modifying therapies. By pairing longer lifespans with vibrant healthspans, we ensure everyone has the energy to pursue what they love and the opportunity to pivot careers at any stage of life.

Source: https://apnews.com/projects/2026-congressional-retirements-tracker/

08/17/2026

🧠 Longevity Fact of the Week

Muscle loss is often thought of as an old-age problem, but the body begins shedding muscle mass as early as our thirties, roughly 3 to 5% per decade, and it accelerates later in life. In other words, healthy aging is something we start winning or losing far earlier than most people realize.

At A4LI, we advocate for a science of aging that helps people protect strength and independence across the entire lifespan, not just at the end of it.

📖 Learn more here: https://www.nia.nih.gov/news/how-can-strength-training-build-healthier-bodies-we-age

08/14/2026

Colorectal cancer has traditionally been associated with older adults. But that is changing.

While colorectal cancer rates are declining among older Americans, they are rising among younger adults. From 2012 to 2021, colorectal cancer incidence increased by an average of 3.8% per year among Americans ages 15 to 39.

The trend has already led to changes in screening recommendations. In 2021, the U.S. Preventive Services Task Force lowered the recommended age for average-risk adults to begin colorectal cancer screening from 50 to 45.

You can learn more here: https://www.cancer.gov/types/colorectal/screening-fact-sheet?utm_source=chatgpt.com

At A4LI, we believe that keeping pace with changes in disease patterns is an important part of advancing public health and improving healthy longevity. As colorectal cancer continues to rise among younger Americans, it raises an important question about how we approach prevention and early detection.

With colorectal cancer rates rising among younger Americans, do you think routine screening should begin even earlier than 45? Why or why not? Let us know in the comments below ⬇️

08/12/2026

Three new presentations from the 2026 H-SPAN Summit D.C. are now live!

This week, we're highlighting three researchers and innovators exploring different approaches to improving human health and addressing the biology of aging:

🧬 Koji Tanabe | Peace, Inc.

Tanabe discusses the potential of induced pluripotent stem cell (iPSC) technology to support regenerative medicine and explore new approaches to cellular rejuvenation, drawing on more than 20 years of iPSC research and development.

🎥 Watch: https://www.youtube.com/watch?v=2HIjlg3w0to

🔬 Ed Schulak | EdenRoc Sciences, LLC

Schulak reflects on more than a decade working in the longevity field, from the early focus on telomeres and genetics to the increasingly sophisticated tools researchers now have to understand the biology of aging.

🎥 Watch: https://www.youtube.com/watch?v=u5MzqvbybxQ

🧪 Christopher Bradley | Matter Bio

Bradley presents MatterBio's approach to developing cancer therapeutics, including a novel strategy designed to target solid tumors and engage the body's existing immune response. He also shares preclinical findings from pancreatic cancer models.

🎥 Watch: https://www.youtube.com/watch?v=fEqneEcOjgc

REMINDER: A4LI Members receive early access to the full 2026 H-SPAN Summit video catalog before each session is released publicly, along with exclusive updates, content, and opportunities to help shape the future of longevity policy.

Become a member today: https://a4li.org/become-a-member

08/11/2026

This week on A4LI’s Scientist Spotlight, we speak with Dr. Christina Stevens, a fourth-year graduate student in Dr. Kylie Kavanagh's lab at Wake Forest University School of Medicine.

In this episode, we discuss her background in veterinary medicine, how she has applied that to aging research, and what has driven her to pursue a career in academia.

Listen to the full episode here: https://a4li.org/podcast/scientist-spotlight-ep-29-dr-christina-stevens/

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