The Alliance for Longevity Initiatives

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Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from The Alliance for Longevity Initiatives, Nonprofit Organization, Washington D.C., DC.

The Alliance for Longevity Initiatives is a 501(c)(4) nonprofit organization focused on advancing legislation, policies and initiatives to increase healthy human lifespan.

10/14/2026

📣 A4LI at the Medical Innovation Olympics

This Friday, October 16, Jonathan Ross, A4LI’s Director of Administration & Operations, will join an expert panel on advancing healthspan extension through science, preventive care, and public policy.

The discussion will explore how policy can support medical innovation, expand access to emerging therapies, and help shift healthcare toward preventing disease and extending healthy lives.

Advancing policies that make this possible is central to A4LI’s mission. We looking forward to contributing to this important conversation.

10/12/2026

Diseases like Alzheimer's, Parkinson's, and ALS can develop over many years, with protein misfolding and clumping contributing to damage in the brain and nervous system. By the time symptoms appear, significant damage may already have occurred. Understanding how these changes begin could open new opportunities to detect and treat disease earlier.

Advanced Research Projects Agency for Health's new BIOGAMI program is tackling this challenge, investing up to $152 million over four years to understand how proteins become dysfunctional and develop ways to intervene. Six research teams, including those at the Buck Institute for Research on Aging, Johns Hopkins, MIT, and UC Berkeley, will combine protein science and computational tools to develop new approaches to early detection and treatment. While the initial focus is neurodegenerative disease, the findings could eventually have applications in cancer, diabetes, and other conditions.

📖 Read more here: https://arpa-h.gov/news-and-events/arpa-h-biogami-program-starts-work-find-and-fix-protein-dysfunction-earliest-stages

At A4LI, we're encouraged to see ARPA-H invest in understanding the underlying biology of disease. The earlier we can identify and address the processes that contribute to age-related conditions, the more opportunities researchers may have to change how these diseases are treated. We'll continue following BIOGAMI's progress and highlighting the work underway at ARPA-H to advance biomedical innovation.

10/09/2026

Many chronic diseases share a common risk factor: the biology of aging itself. What if targeting that biology could help prevent or delay multiple diseases at once?

The National Institutes of Health (NIH) Geroscience Interest Group and the National Institute on Aging - NIH will host the Fifth Geroscience Summit, Revisiting the Geroscience Hypothesis: Focus on Health, bringing together researchers, clinicians, and other stakeholders to advance the field and shape its research priorities for the next 3 to 5 years.

Across two days, discussions will explore emerging areas of geroscience, approaches to measuring healthspan, and opportunities to accelerate the development of gerotherapeutics.
📍 Building 35, NIH Main Campus, Bethesda, MD (virtual attendance also available)
🗓️ December 2–3, 2026
⏰ Dec. 2: 8:00 a.m.–4:45 p.m. ET | Dec. 3: 8:00 a.m.–5:00 p.m. ET

📖 Learn more and register here: https://www.nia.nih.gov/research/dab/workshops/fifth-geroscience-summit-revisiting-geroscience-hypothesis-focus-health

At A4LI, we believe targeting the underlying biology of aging could help prevent or delay multiple chronic diseases and transform how we approach human health. Turning that potential into better outcomes will require continued scientific progress alongside policies that accelerate therapeutic development and expand patient access.

We look forward to seeing the geroscience community help shape what comes next for healthspan.

10/06/2026

Looking for a way to celebrate International Longevity Month this weekend?

Join A4LI and Dr. Barry Breaux, Co-Founder of Longevity for the People, for a morning hike through Reinhardt Redwood Regional Park in Oakland this Saturday, October 10.

Come get some movement, fresh air, and good conversation with others interested in building a longer, healthier future. Whether you're already part of the longevity community or simply looking for a reason to get outside, we'd love to see you there.

📍 Oakland, CA
🗓️ Saturday, October 10, 2026

RSVP: https://luma.com/6yknf2vo

Learn more about Longevity for the People: https://longevityforthepeople.org/

10/02/2026

Bringing a new drug to patients typically takes more than a decade and costs around $2 billion, and about 90% of candidates fail along the way. Much of that time and cost comes from a rigid, phase-by-phase clinical trial process that has changed little in decades.

Advanced Research Projects Agency for Health's new SURPASS program aims to change that. It uses digital twins, predictive modeling, and real-time data analysis so trials can adapt as evidence comes in, rather than waiting for each phase to finish. SURPASS launched alongside three other HHS efforts to expand clinical trial sites, build privacy-protected data infrastructure, and give patients a greater role in research. Together, these efforts could mean shorter timelines, lower costs, and fewer participants needed to reach clear answers.

📖 Read more here: https://arpa-h.gov/news-and-events/hhs-launches-surpass-and-new-efforts-accelerate-faster-smarter-clinical-trials

At A4LI, we are proud to see ARPA-H take on one of the biggest bottlenecks in modern medicine. The faster we can generate reliable evidence, the sooner promising therapies for age-related disease can reach the people who need them. We will keep advocating for a research and regulatory system built for the speed of today's science, and we look forward to following SURPASS as it moves forward.

10/01/2026

Happy International Longevity Month! 🧬

For A4LI, this month is a chance to celebrate the scientists, researchers, entrepreneurs, advocates, policymakers, and everyone else working to make longer, healthier lives a reality.

Longevity science is moving quickly, and there is still a lot we don’t know. But every new discovery, clinical trial, policy conversation, and breakthrough brings us a little closer to understanding how we can extend not just lifespan, but healthspan.

We are proud to be part of this growing community and excited for what’s ahead.

Over the coming weeks, we will be connecting with the longevity community at events happening during Boston Longevity Week that starts today, and then hopping back to California Bay Area for our own longevity hike, Roundtable of Longevity Clinics, and Longevity Partnering Forum.

Follow along for updates from the events, conversations, and people shaping the future of longevity.

Boston Longevity Week: https://www.bostonlongevityweek.com/
A4LI Longevity Hike: https://luma.com/6yknf2vo
Roundtable of Longevity Clinics: https://longevity-roundtable.com/
Longevity Partnering Forum: https://www.longevitypartnering.com/

09/28/2026

Many cell-based therapies, including treatments for cancer and autoimmune disease, currently rely on storage at temperatures as low as -196°C. Maintaining that ultra-cold supply chain adds significant costs and can make these therapies harder to deliver where they are needed most.

Advanced Research Projects Agency for Health’s new BioStabilization Systems (BoSS) program is taking on that challenge, investing up to $87 million to develop technologies that could keep life-saving cell therapies stable at room temperature.

A 200-degree leap could mean more than eliminating freezers. It could help lower costs, simplify distribution, and make advanced therapies more accessible to patients and providers, including at community hospitals.

📖 Read more here: https://arpa-h.gov/news-and-events/arpa-h-teams-prepare-take-200-degree-leap-and-end-cold-chain-dependence-life-saving

At A4LI, we’re excited to see ARPA-H tackle the infrastructure challenges that can stand between scientific breakthroughs and the patients who need them. Innovations that make advanced therapies easier to manufacture, transport, store, and administer will be an important part of building a health system capable of delivering the next generation of medicine.

As A4LI continues to advocate for policies that accelerate longevity and biomedical innovation, we look forward to highlighting more of the work underway at ARPA-H and across the biomedical research ecosystem.

09/22/2026

This Thursday, September 24, the Senate HELP Committee will convene a confirmation hearing on the nomination of Dr. Heidi Overton to be FDA Commissioner. A4LI has submitted key policy questions to the HELP Committee to ensure the FDA’s future leadership prioritizes regulatory frameworks for multi-disease and aging therapeutics.

As the agency regulates the next generation of interventions, strong leadership at the FDA is critical to modernizing drug development pipelines for healthspan.

▶️You can watch the full hearing here: https://www.help.senate.gov/hearings/nomination-of-heidi-overton-to-be-commissioner-of-food-and-drugs

09/21/2026

When a cell comes under stress, it can take several paths: repair itself, enter a dormant state, become a senescent cell, or die.

How those decisions are made, and whether they can be redirected, is still an open question in aging research. National Institutes of Health (NIH)’s newest priority asks scientists to map the biology behind these cell-fate decisions, with the goal of building a stronger foundation for more precise therapies for aging and age-related disease.

This is the kind of foundational question that sits underneath much of the aging research already underway, including senolytic drugs designed to eliminate senescent cells. A clearer understanding of how cells enter and move between these states could help researchers develop more targeted approaches.

🔗 Link here: https://grants.nih.gov/funding/find-a-fit-for-your-research/highlighted-topics/89

At A4LI, we’re encouraged to see NIH investing in the fundamentals of aging biology. The better we understand how cells respond to stress and aging, the better positioned we are to develop the next generation of interventions.

09/18/2026

Celebrate International Longevity Month with a hike through Reinhardt Redwood Regional Park! A4LI is teaming up with Dr. Barry Breaux, Co-Founder of Longevity for the People, for a morning of movement, fresh air, and good company.

Whether you're deep into the longevity world or just love a good excuse to get outside, this one's for you.

📍 Oakland, CA | 🗓️ October 10th, 2026

RSVP here: https://luma.com/6yknf2vo

Learn more about Longevity for the People: https://longevityforthepeople.org/

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http://a4li.org/

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