03/09/2026
New study explores intranasal administration of mother’s milk in babies after hypoxic ischemic encephalopathy?
The rationale is compelling: human milk contains stem cells, growth factors, anti-inflammatory mediators, and neurotrophic factors, and intranasal delivery may allow biologically active components to reach the brain through olfactory pathways.
Treatment tolerated in all 10 babies in this pilot study
Many mechanisms involved in preterm IVH overlap with hypoxic-ischemic encephalopathy (HIE) in term infants—neuroinflammation, oxidative stress, and impaired repair.
Could intranasal mother’s milk become a simple adjunctive neuroprotective therapy for term infants with HIE?
https://pubmed.ncbi.nlm.nih.gov/41776367/
