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CHAI's mission is to save lives and improve health outcomes in low- and middle-income countries by enabling the government and private sector to strengthen and sustain quality health systems.

08/13/2026

CHAI is partnering with Freddie, a leading 2SLGBTQ+ telehealth platform in Canada and the US, to launch PrEP ONWARDS— a new model where every new PrEP sign-up at Freddie also funds a six-month dose of lenacapavir for someone in an early-adopter country in Africa.

Lenacapavir, the twice-yearly injectable HIV prevention shot, has the potential to end HIV as a public health threat in Africa. But today, fewer than one in four people who could benefit from PrEP currently have access to it.

Freddie is funding this work through its own patient growth in North America; support that CHAI will use getting lenacapavir into countries as quickly as possible.

For more than two decades, CHAI has worked directly with governments and health systems to bring down the cost of HIV medicines and help new products reach people faster. We're bringing that same experience to lenacapavir because getting it to people quickly, in the places that need it most, is what will determine how many lives this can change.

Learn more: https://ow.ly/uMZR50ZyE5n

08/11/2026

CHAI has secured a new price of US$32.50 per box for Ready-to-Use Therapeutic Food (RUTF) — the peanut-based paste that's the standard treatment for severe malnutrition in young children.

Indian manufacturer Vista Fortifoods has committed to the price for governments, NGOs, and humanitarian agencies across dozens of low- and lower-middle-income countries. It's 30% below the global average, and the lowest price available today.

As acute hunger continues to rise worldwide, this deal can have real impact: even a modest 10% shift in current spending toward this price would be enough to reach a million more children with treatment, without a single new donor dollar.

This builds on CHAI's work in Ghana, where a similar price reduction helped the country more than double the number of malnourished children receiving treatment.

Read more: https://ow.ly/Qyf750ZyCm9

Ministry of Health, Ghana

08/04/2026

Last week, on World Hepatitis Day, we shared a decade of evidence: a 88% drop in the cost of a hepatitis C cure, and a country — Rwanda — near elimination.

But progress is fragile.

WHO's elimination targets call for an 80% drop in new hepatitis C infections and a 65% drop in deaths by 2030. A decade since those targets were set, deaths have fallen just 12%, and new infections just 8%.

The reason isn't a lack of tools. It's fragmented procurement pushing treatment prices back up, tightening health budgets, and a financing model that, unlike HIV or malaria, has no predictable architecture countries can plan against.

Our report lays out five priority investments to close that gap: finishing the job in countries closest to elimination, finding the millions already diagnosed but never treated, protecting the pricing agreements that made a cure affordable, integrating hepatitis C into routine health systems, and helping governments transition to sustainable domestic financing.

Sustaining what's already built is far cheaper than rebuilding it once momentum is lost.

Read the full report: https://ow.ly/Xpq550ZuCnZ

07/28/2026

A complete cure for hepatitis C costs under US$60. Yet, it still kills about one person every two minutes.

Not because the science is missing. Because the political commitment and financing to deliver that cure at scale haven't followed.

Since 2016, CHAI has partnered with ministries of health in Cambodia, India, Indonesia, Myanmar, Nigeria, Rwanda, and Vietnam to bring hepatitis C testing and treatment into public health systems. The results:

➡️ 25.4 million people screened
➡️ 473,000 people cured
➡️ 159,000 premature deaths averted
➡️ The cost to cure dropped 99%

This World Hepatitis Day, we're sharing what a decade of implementation taught us—and what it will take to finish the job. Rwanda is on the verge of eliminating hepatitis C entirely. The next decade will decide whether the rest of the world gets there too.

Read the full report: https://ow.ly/3AnY50ZtB1i

07/21/2026

At (July 26–31, Rio de Janeiro), CHAI will spotlight two of the defining stories in HIV right now: the rollout of long-acting lenacapavir for PrEP, and how governments are stepping up to lead HIV programs through declining donor funding.

On lenacapavir, our teams will share early lessons from introduction in Zambia, Nigeria, Mozambique, Uganda, and Eswatini: from rapid policy development and demand generation to real-world outcomes and market shaping to expand access.

On sustainability, look for our satellite session "Resilience in action: Government-led strategies for sustaining HIV programs as aid declines," alongside sessions on program integration and advanced HIV disease care as countries adapt their systems for the road ahead.

See the full list of CHAI sessions at AIDS 2026: https://ow.ly/S68J50ZqafE

Unitaid, World Health Organization (WHO), Gates Foundation

07/20/2026

Big news: Unitaid and CHAI have struck new agreements with DeepTek Inc and Delft Imaging that cut the cost of AI-powered TB screening software by up to 65%.

TB remains the world's deadliest infectious disease, and chest X-rays are essential for catching it early — but in the countries hit hardest, a severe shortage of radiologists (as few as one per million people in some places) has stalled screening programs. AI-powered software solves this by reading X-rays instantly, performing on par with a trained radiologist, so people can get results the same day even without a specialist on-site.

"TB is curable, but only if you catch it," said Dr. Neil Buddy Shah, CEO of CHAI. "AI-powered software can now do that in seconds, and this agreement makes it far more affordable, dramatically increasing the number of people who can be diagnosed and put on treatment."

Combined with 2025's price cuts on portable X-ray devices, programs can now deploy a complete AI-powered TB screening solution at a fraction of the previous cost.

Read more: https://ow.ly/lAiq50ZqakE

KNCV Tuberculosis Foundation, PATH, London School of Hygiene & Tropical Medicine

07/15/2026

There is no treatment for Bundibugyo Ebola today. Clinical trials for the first potential therapeutics just started and results won't arrive for 18+ months. Even then, history shows us approval doesn't mean access: countries typically wait months or sometimes years before they can actually deploy life-saving treatments. Given the Ebola cases spreading across the DRC and Uganda right now, we can't afford that delay.

We also can't afford diagnostic delays. This outbreak went undetected for weeks because there were no diagnostics able to detect Bundibugyo Ebola, allowing cases to spread unchecked. New diagnostics are now being urgently developed and validated, and will be critical for scaling case detection and contact tracing in the coming weeks.

It's why Unitaid announced US$3.4M last week to accelerate access to both promising diagnostics and medicines. And why CHAI's work is at the center of it: forecasting demand, securing supply chains, and positioning access pathways. So the moment efficacy data arrives—for treatments and diagnostics alike—countries can deploy these tools immediately.

https://ow.ly/saoN50ZnSu0

07/09/2026

AI is moving faster than almost any technology we've seen in global health but speed alone won't make it work for everyone.

Most AI tools today are built on data, languages, and infrastructure from high-income countries. That means a developer building a health tool in Ghana or Mozambique is often starting from scratch—no benchmarks for their patient population, no relevant data, no standards to build on.

That's why CHAI, the Agency Fund, and Endless Global have launched the AI Commons for Global Health, a shared initiative born out of a convening at the Rockefeller Foundation's Bellagio Center, bringing together innovators, frontier AI labs, funders, and global health practitioners around one question: what will it take for AI to actually improve health outcomes everywhere, not just where the data and money already are?

Four working groups are underway, building open resources for:
🔹 Data exchange: a fair marketplace for low- and middle-income country health data, with privacy tools built in
🔹 Clinical decision support architecture: a free blueprint so innovators don't have to start from zero
🔹 Evaluations: practical tools to test whether AI tools really work in context
🔹 Procurement: reusable guidance for governments buying AI solutions

We're at the beginning, and this will only be as strong as the community that shapes it. If you're building AI for low-resource health settings, working on evaluation or data governance, advising governments, or funding this space, we want to hear from you.

Learn more and get in touch-->
https://ow.ly/Xmut50Zm9Yo

07/01/2026

When healthcare costs more than a family can afford, every visit becomes a decision between care and survival. In six Nigerian states, that calculus is changing. Through a partnership between the Government of Canada (via Canada’s International Trade - Global Affairs Canada) and CHAI, health insurance coverage for vulnerable women and children grew 301% — from roughly 280,000 people to over 1.1 million. Most of that growth is now state-funded, built on systems designed to outlast the original investment. Watch the story, then read more. https://ow.ly/N1Ts50ZiOMQ

06/19/2026

Today is . SCD is one of the most common and most painful genetic disorders in the world, yet it remains chronically underfunded and overlooked. In Ghana alone, an estimated 18,000 babies are born with the disease every year. Up to 90% of them may die before age five. Not because treatment doesn't exist, but because they won't get screened in time.

That's exactly why we made screening a focus of our program.

With catalytic funding from Coefficient Giving, we've been able to demonstrate what's possible: 50,000 test kits donated, 66,800 more on the way, and a program projected to save over 1,500 lives. But proof-of-concept isn't enough. The goal has always been to move this into Ghana's national health system, fully implemented, fully covered, no out-of-pocket costs for families.

That's what we're building toward. Because children with sickle cell disease need systems that show up for them.

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