04/06/2026
News from the PANGEA Study at Dana-Farber Cancer Institute: Which Smoldering Myeloma (SMM) Patients Are More Likely to Progress? Inside the PANGEA-SMM Model.
The PANGEA Model is a tool that helps patients predict their personal risk of developing myeloma within the next 1 to 10 years. The model incorporates both patients' most recent lab results and their lab history from the past two years to provide a more individualized risk estimate. The PANGEA model is available to anyone who wants to use it on the website: https://pangeamodels.org/
Read the Nature Medicine paper describing the model: https://www.nature.com/articles/s41591-026-04304-x
Learn how the PANGEA model was developed in this article by one of its creators: https://communities.springernature.com/posts/how-we-built-pangea-smm-to-predict-progression-to-myeloma
