Myelin Repair Foundation

09/20/2019

Dear Friends and Supporters,
We have an important update to share with you: Based on data from our investigations to date and counsel from our advisors, we are dedicating our next fiscal year (which started July 1) to research on extracellular vesicles (EVs). EVs are a promising area that, while recently exploding in cancer research, have not yet been exploited in neurological diseases, like MS. Yet early research indicates that EVs may play a role in myelin formation.

Learn more about why we feel EVs hold such promise, and why we are so excited:

The Myelin Repair Foundation is an innovative research foundation focusing on developing drug therapies for multiple sclerosis patients.

05/01/2015

Check out this story, "How a white powder couldn't pass U.S. Customs but could save MS patients" - an inside look into what the MRF faced with getting guanabenz (MRF-008) into clinical trials.

The nonprofit Myelin Repair Foundation in Saratoga and the National Institutes of Health will take an out-of-production, generic high blood pressure treatment into a clinical trial in multiple sclerosis.

04/30/2015

This just in: exciting news about the much-anticipated guanabenz (MRF-008) clinical trial!http://www.myelinrepair.org/documents/Guanabenz_MRF-008_Press_Release_FINAL_04-30-2015.pdf

04/24/2015

Talk about an inspirational woman, and a great MS awareness video! We very much enjoyed watching Kaleigh's video and call for action, check it out!

(Warning: contains some minimal adult language.)

For information about MS and how you can donate: http://www.nationalmssociety.org/ To donate to Team Kaleigh for her WALK MS campaign: http://main.nationalms...

04/21/2015

Exciting new research out of MRF-funded labs this week!

"Two drugs already on the market — an antifungal and a steroid — may potentially take on new roles as treatments for multiple sclerosis. According to a study published in Nature [...] researchers discovered that these drugs may activate stem cells in the brain to stimulate myelin producing cells and repair white matter, which is damaged in multiple sclerosis."

http://www.nih.gov/news/health/apr2015/ninds-20.htm

NIH-funded study identifies over-the-counter compounds that may replace damaged cells

03/13/2015

The latest from our lab at the University of Chicago regarding MRF's recent projects and clinical development: researchers from the University of Chicago show that an FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of MS in animal models.

"A recent study found evidence that guanabenz, a drug approved for oral administration for hypertension, enhances this stress response pathway independent of its anti-hypertension actions.

The Myelin Repair Foundation — which funded this work and supporting studies as part of a long-term, multi-institutional effort to identify potential therapeutics — has entered into a cooperative agreement with the National Institutes of Health to assess guanabenz as a therapeutic candidate in MS clinical studies."

Guanabenz, an FDA-approved drug for hypertension, appears to prevent myelin loss and alleviates symptoms of MS by enhancing innate cellular protective response, according to a new study by scientis...

03/11/2015

How are you educating others about multiple sclerosis and myelin repair this month? Take a moment to start a conversation by adding this "I heart myelin repair" badge to your profile! Then be sure to tell your friends what it means, and why you're supporting the Myelin Repair Foundation this March!

The Myelin Repair Foundation (MRF) is a non-profit research foundation focused on rapidly developing effective myelin repair treatments for multiple sclerosis patients in need. Myelin is the fatty protective coating surrounding nerve fibers...

03/02/2015

March is officially here and that means it is time for Multiple Sclerosis (MS) Awareness Month! Here at the MRF March is a great opportunity for our supporters to get more involved by helping spread the word about MS and myelin research to their friends and family. Join us this month in educating others and supporting this critical research, and stay tuned for more ways to get involved!

In the meantime we'd love to hear from you: What is one thing you plan to do in March for MS Awareness Month?

02/09/2015

In case you missed it: iConquerMS is a new website geared towards conquering MS through the sharing of patient symptoms and experiences.

While the MRF is working hard to produce breakthrough medicines to treat this debilitating disease, there's still a lot we don't know about its cause or variations in severity. Information sharing and collection could help address just that.

Check them out to learn more about the importance of information collection in tackling diseases: https://iconquerms.org/about

People living with multiple sclerosis can play a major role in conquering this disease. When you contribute your health information and share your ideas about topics you care about, you enable researchers to better understand, treat, and ultimately cure MS.

01/01/2015

Happy New Year to all of our amazing, dedicated supporters! A new year, and you know our team at the Myelin Repair Foundation can't wait to dive right in. As always, we will be feeding you the latest research updates and breaking news alerts as they happen... so stay tuned for more from us in the coming months! We look forward to keeping you up-to-date on our progress in 2015. :)

12/31/2014

Okay, the last day of the year is officially here! If you haven't already made a gift to the Myelin Repair Foundation in 2014, please consider getting in your last-chance, tax-deductible gift today. Only hours to go before we will be ringing in the New Year, so help us finish this awesome year off strong! (Oh, and did we mention that it will be matched?) Donate here now: http://bit.ly/SupportMRF

12/31/2014

Can you believe we have just over a day to go before 2014 is over? Tomorrow is your absolute last chance to make a tax-deductible gift to MRF in 2014 and help us end this year strong! If you are able, please make a charitable gift of support today and help us make an impact for MS patients in need: http://bit.ly/SupportMRF