Middle Finger To Cancer

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Maryville, MO
Middle Finger To Cancer

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In the summer of 2015, Trent Twaddle, MF2C's founder, was a seemingly healthy 32 year-old financial analyst living with his new wife in Houston, Texas.

MF2C stands with patients seeking treatment for sarcoma cancers of the limb, providing benevolent assistance to lessen their burden and help them fight their battle. Following his wedding in May, Trent was seen by an orthopedic surgeon to evaluate a small lump in the palm of his right hand. The lump was first noticed in April of 2015 and was thought to perhaps be a common fibroma. After several weeks of physical therapy and no improvement an MRI proved to be suspicious of a tumor. A core needle biopsy was taken at MD Anderson July 31st. The Division of Pathology studied the tissue specimen and results were returned August 14th. Trent was informed that the lump in his hand was a sarcoma. More specifically, it was a Myxoinflammatory Fibroblastic Sarcoma. The doctors at M D Anderson informed him that amputation of his right hand at mid-forearm was the treatment of choice. After the initial shock, thoughts turned to locating someone for a second opinion. Dr. Ed Athanasian, MD at Memorial Sloan Kettering was seen by Trent September 14th . Dr. Athanasian confirmed the diagnosis but suggested a possible alternative to immediate amputation…Isolated Limb Perfusion with Tumor Necrosis Factor-Alpha (TNF-a). By this time Trent had lost most of the normal function of his right hand. As TNF-a is not available in the U.S., Trent’s next stop was Paris France where he was hospitalized at Institute Gustave Roussy. On October 20 th , in a 7-hour procedure, a mixture of TNF-a and Malphan was delivered to the tumor via Isolated Limb Perfusion. Trent returned to the New York in December for a 5-week course of Radiation Therapy. March 11, 2016 an MRI at Memorial Sloan Kettering revealed remarkable shrinkage of the tumor mass. He had also regained most of his right hand function and dexterity. Dr. Athanasian performed surgery on March 16 th to remove the remains of the sarcoma. The importance of removing the entirety of the tumor with clean margins necessitated the amputation of his middle finger. The biopsy report found absolutely no remaining cancer cells. Trent continues to return to Memorial Sloan Kettering every 4 months for scans and will continue to do so for a number of years. All reports to date are very good and promising. Trent wishes to share this story to encourage those with similar diagnoses to follow his path of second opinions and the hope for a cure. Tumor Necrosis Factor-alpha is an important treatment adjunct and we encourage its use in the United States. TNF-a in Isolated Limb Profusion is a sarcoma treatment with 20-plus years of success in Europe. It is long past time for the drug manufacturers to submit it to the FDA for U.S. approval. Trent Twaddle is an avid golfer, having competed as a scholarship athlete for the University of Missouri. Minus his middle finger, Trent has returned to competitive golf and in the summer of 2017 competed in qualifying rounds for the U.S. Mid-Amateur Championship. Through the power of God, the power of prayer and God’s guidance of the hands and hearts of great doctors and nurses all things are possible. Trent truly gave the “Middle Finger to Cancer!”

"I'm really grateful for all of the great friends and support I have received while battling cancer and starting the Middle Finger To Cancer organization. It is now my goal to pay everything that I can forward to those that are in a similar situation that I was and to cancer research."

- Trent Twaddle

05/11/2026

A huge thank you to everyone that came out to Mozingo Lake Golf course to support the 8th annual Middle Finger To Cancer Golf Challenge. We appreciate your participation, donations, and continued support each year. It was a great day in every way! A sincere thank you to this year’s corporate sponsors - Compass Dental, Nodaway Valley Bank and Scobee Powerline Construction. Thank you to the golf course staff and Lake Tavern 75 for making the tournament run smoothly and effortlessly! Last, congratulations to this year’s championship team of Twaddle, Twaddle, Beard and Croy with a score of 55! We’re already looking forward to next year’s event!

04/23/2026

We hope to see you at Mozingo Lake Golf Course! Registration link in comments.

05/15/2025

Thanks to Sports Editor Jon Dykstra and the Maryville Forum for the fantastic article!

MARYVILLE, Mo. — Trent Twaddle’s love for golf led to an alarming discovery in the summer of 2015. The 32-year old realized there was something off with his hand as

05/10/2025

The 2025 Middle Finger To Cancer Golf Challenge is in the books. It was a beautiful day! Thank you to everyone that came out to support the event - players, volunteers, Mozingo staff members, and especially this year's sponsors. You are appreciated. We're already looking forward to next year's event!

05/09/2025

Today is the day! We're teeing it up at Mozingo Lake Golf Course in Maryville, MO! We're excited to see everyone that has registered to play and support MF2C. For those that can't attend, we have some fantastic online auction items up for grabs. Check out the auction and make your bid at:

https://play.eventcaddy.com/guest/auction/list?token=eyJhbGciOiJIUzI1NiJ9.eyJpYXQiOjE3NDY2NzExMDgsImp0aSI6IjE3NDY2NzExMDgvMmZiODI1YTdkZjNmYWI0MzFiMzA0YWNjNGM0YjZmMzUwNTAyIiwidG91cm5hbWVudF9pZCI6NjQ3ODgsImV4cCI6MTc3ODMwNTc1Mn0.Ro7qqiI0OfTCy_NnCupAlsiNxNmiV5HA0PSv5RX1U0w&tournament_id=64788

03/14/2025

Get ready to swing (clubs and paddles!) into action and show cancer the way out! We're excited to invite you to the 2025 Middle Finger To Cancer Houston Shootout and Pickleball Tournament at the East River 9!

Pickleball ($400): Team includes entry for a team of 2 into the Middle Finger To Cancer Pickleball tournament, beverages, MF2C swag and dinner following the event.

Golf ($700): Team includes 9 holes of golf for 3 golfers competing in best ball format. Entry includes range balls, beverages, MF2C swag and dinner following the event.

Register today! https://app.eventcaddy.com/events/houston-shootout-pickleball-tournament?mc_cid=345c89e818&mc_eid=dd2ada18f5

02/03/2025

You're Invited! ⛳🏓

Join us for a fun day of golf and pickleball! Whether you're a seasoned player or just looking to have a good time, we'd love to have you there.

📅 Date: Thursday, April 10th, 2025
📍 Location: East River 9 (65 Hirsch Road, Houston, TX)
⏰ Time: 3pm Check-in - 4pm Sh***un Start + Pickleball Tournament
✅ Regististration: https://app.eventcaddy.com/events/houston-shootout-pickleball-tournament

Come for the games, stay for the laughs - let’s make it a day to give the middle finger to cancer! Register today and let us know if you’ll be swinging, smashing, or both!

All proceeds go towards patients seeking treatment for sarcomas of the limb, providing benevolent assistance to lessen their burden and help them fight their battle.

See you on the course and the court!

01/01/2025

🎉 Cheers to new beginnings! Here's to a year filled with happiness and endless possibilities. Let's make 2025 unforgettable! 🥂✨

12/25/2024

Dear Friends and Supporters,

This Christmas, we raise our glasses high with a bold "Middle Finger to Cancer!" 🎄✨ In the face of every challenge, your steadfast support has been our beacon of strength. As we come together this holiday season, we’re not just celebrating the festivities—we’re celebrating resilience, hope, and the unbreakable bond that unites us all.

May this season bring you warmth, joy, and the comfort of loved ones who uplift and inspire. As we exchange gifts and share laughter, let’s remember that each moment is a victory, and every act of kindness is a reminder of the power of unity.

As the new year approaches, may hope shine even brighter, and may our collective determination continue to rise above every challenge. Together, we send a powerful message: love, support, and the human spirit are unstoppable forces.

Wishing you a Merry Christmas filled with love, joy, and the promise of brighter days ahead.

Here’s to resilience and our relentless fight against cancer!

Cheers!

12/04/2024

Please save the date! New, exciting format in 2025! 3-person best ball golf + pickleball! Registration link coming soon.

Address

Maryville, MO
64468

Website

https://middlefingertocancer.org/

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