08/25/2025
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Scientists at the University of Florida have developed a groundbreaking mRNA cancer vaccine that wiped out aggressive brain tumors in early human trials—without the need for chemo or radiation.
Tested on four glioblastoma patients, the personalized vaccine reprogrammed their immune systems in just 48 hours to target and destroy tumor cells. Using each patient’s own tumor material, the treatment was delivered via lipid nanoparticles and showed results consistent with earlier success in mice and dogs. The vaccine is now advancing into Phase 1 pediatric trials.