Ambria Tall is a wonderful, 8 year old, little girl who was recently diagnosed with C.M.L., shortly after her 8th birthday. She is a life long resident of Jennings. Here is a little more information about her cancer...Chronic myelogenous leukemia, also known as chronic granulocytic leukemia, is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulat
ed growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes and their precursors is found. It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome. CML is now largely treated with targeted drugs called tyrosine kinase inhibitors which have led to dramatically improved long-term survival rates since the introduction of the first such agent in 2001. These drugs have revolutionized treatment of this disease and allow most patients to have a good quality of life when compared to the former chemotherapy drugs. In Western countries it accounts for 15-20% of all adult leukemias and 14% of leukemias overall.
