04/19/2022
Happy Bicycle Day! 🚲👁🚲
+ While working on lysergic acid derivatives, Albert Hoffman first derived L*D-25 by reacting lysergic acid with diethylamine, a derivative of ammonia on November 16th, 1938.
+ Trying to reexamine L*D-25 on April 16th, 1943, Hoffman accidentally spilled some on his fingertips and discovered its effects. April 19th, 1943 Hoffman intentionally took 250 μg and had his first trip start on a bicycle ride. This us seen as the first intentional L*D trip.
+ Hoffman also isolated psilocybin and psilocin from the mushroom (Psilocybe mexicana) in 1959. In 1960, Hoffman discovered LSA in morning glory (Rivea corymbosa). In 1963, Hoffman set out to southern Mexico to find samples of Ska Maria Pastora (Salvia divinorum), but never found the active compounds.
