10/13/2026
Researchers at the Cornell University College of Veterinary Medicine and the Baker Institute for Animal Health have documented the first-ever molecular characterization of Marfan syndrome in domestic cats โ published in the September 19 issue of Scientific Reports. ๐ฌ
Meet Gary and Shaggy ๐พ feline siblings whose unusually long limbs as kittens, combined with later eye abnormalities and an enlarged aorta, led veterinarians to suspect Marfan syndrome, a rare connective tissue disorder best known in humans (affecting ~1 in 4,000 people). This marks the first documented case in cats!
Through genetic sequencing, the team discovered that both brothers carried two altered copies of the FBN1 gene โ which codes for fibrillin-1, a key building block of connective tissue found in blood vessels, bones, skin, and eyes. ๐
This discovery brought together veterinary specialists and geneticists from Cornell, Ghent University (Belgium), the University of Pennsylvania, and The Schwarzman Animal Medical Center in NYC. ๐
Read more: https://www.vet.cornell.edu/about-us/news/20260922/first-known-cases-feline-marfan-syndrome-discovered-cat-siblings