10/15/2026
A new piece of the Batten disease puzzle, revealing connections across multiple forms.
We are glad to share important new research, jointly funded by the Batten Disease Global Research Initiative (BDGRI) and NCL Stiftung, published in Nature Cell Biology.
Led by Dr Kasparas Petkevicius at the University of Cambridge, the research reveals that CLN8 plays a key role in producing BMP, a specialised fat molecule that helps keep lysosomes, the cell's recycling centres, working properly. The study shows that CLN8 and CLN5, two different Batten disease proteins, work together to make BMP.
Researchers also showed that the biochemical defect caused by loss of CLN8 could be bypassed experimentally, an early foundation for future therapeutic research across multiple NCL forms.
Congratulations to Dr Petkevicius and team.
Read the summary and the article here: https://tinyurl.com/3m2fvbd9
