Joshua's Future Of Promises

08/20/2026

The IFOPA is pleased to share breaking news-approval of Regeneron's drug in the US! Thanks to all who took part in the trial! 💙💚

💡 Do you know what Pasatru™ is?
It is the brand name for Regeneron's drug garetosmab, which has been approved today in the 🇺🇸 United States to treat FOP.

Pasatru™ (garetosmab) is only the second drug approved for FOP in the U.S., and the first shown to have an impact on both bone growth and flare-ups.

As we announce this decision, we are deeply grateful to people living with FOP from around the world who participated in two pivotal trials of garetsomab: LUMINA-1 Phase 2 and OPTIMA Phase 3 🙌

We also want to thank Regeneron and its employees for their long-standing commitment and dedication to the FOP community. This drug was invented by scientists at Regeneron who were looking for ways to treat FOP by blocking heterotopic bone growth 👏

📌 Learn more and read Regeneron’s press release: ifopa.org/garetosmab-fda-approval

Congratulations to the FOP community on this very special day! 💚💙

06/27/2026

What an AWESOME night at the Luke Bryan concert! 🎶🎤🎸

Josh had lots of fun and even ran into (& got a picture with) one of the openers, Shane Profitt. 🤠

06/25/2026

First of many concerts this year for Joshua! 🎶🎤🎸

Luke Bryan @ PPL Center in Allentown 🤠

06/03/2026

Buy Pizza, Raise Dough! 🍕💸

Don't forget to use our code when you purchase Papa John's pizza!

Use "JFOP" to receive a discount AND support our cause! Fundraising never tasted so delicious! 😋

*Only at select locations*

05/12/2026

This is exciting news for the FOP community! 💙💚

Mirum Pharmaceuticals announced that it has acquired the rights to zilurgisertib, a drug currently being studied as a possible treatment for FOP in the PROGRESS Phase 2 trial.

Even more encouraging, results from Part 1 of the trial (patients ages 12+) have been submitted to the FDA and granted Priority Review (meaning the review process will move faster than normal). The FDA is expected to make a decision by September 26, 2026.

The Scoble family is beyond grateful for your support for the past 19 years. A large portion of the funds donated to Joshua’s Future Of Promises have helped us reach this research milestone. Your donations are making a difference. Thank you to everyone who has supported our cause. 💙💚

For more information, visit ifopa.org.

We’re expanding our commitment to the rare disease community.

Mirum has in-licensed exclusive worldwide rights to zilurgisertib, an investigational oral therapy in development for fibrodysplasia ossificans progressiva (FOP)—an ultra-rare genetic disease, from Incyte.

The FDA has accepted the NDA for zilurgisertib and granted Priority Review, with a PDUFA date of September 26, 2026.

This moment reflects years of progress driven by the FOP community, and we’re honored to add our voice to that foundation.

For patients living with FOP and their families, new treatment options cannot come soon enough. We’re committed to working with urgency to bring this potential therapy forward.

05/10/2026

PHILADELPHIA POWERPLAY WINS!!! 🧡🏆🖤

PowerPlay crushed the Ontario Outlaws 9-3 in the final match.

Joshua is so excited to be part of another championship win! 💪

We’re so incredibly grateful for this team and all the new friends and families we’ve met along the way. Joshua loves playing hockey and we love cheering him on. Here’s to another amazing season! 🍾

Congrats Philadelphia PowerPlay! 🧡🖤🎉🏒👏🏆

05/10/2026

The Flyers PowerPlay defeat the Toronto Toros of PowerHockey Canada 7-2 in the final game of round robin play. The team will compete in the Cambridge Floorball Club Oxdog Open Final at 12:45PM.

| Dorman Products

05/10/2026

Game #4: Philadelphia PowerPlay defeats Toronto Toros again 7-2 in their morning game 🏒💪

PowerPlay remains undefeated as they head to the Championship game at 12:45 today…

GO POWERPLAYYY!!! 🖤🧡🖤🧡

Video below is of Josh’s teammate, Nate, with an awesome save between his legs 🤣

05/09/2026

The Flyers PowerPlay shutout the Ontario Outlaws 8-0 to finish Day 1 of the Cambridge Floorball Club Oxdog Open with a perfect 3-0 record.

| Leahy Life Plan

05/09/2026

Game #3: Philadelphia PowerPlay defeat Ontario Outlaws again with a final score of 8-0!

That’s a whole day of wins for Joshua’s team! 💪🧡🖤🏒

Tomorrow, his team will play one more game before the championship match.

GO ORANGE & BLACK 🎉

⬇️ Below is a quick video of Josh scoring a goal in the third game!