06/24/2026
⚠️ A new and even more dangerous synthetic opioid is reaching Cleveland.
A recent Signal Cleveland investigation highlights the rise of nitazenes, an emerging class of synthetic opioids that can be even more potent than fentanyl and are increasingly showing up in Ohio’s drug supply. Ohio has recorded the highest number of nitazene-related overdose deaths in the country since 2021, with Cuyahoga County among the hardest hit.
This is a sobering reminder that the overdose crisis continues to evolve and become more complex. These substances are often mixed into other drugs without users knowing, increasing the risk of accidental overdose and making prevention even more urgent.
For Cleveland, this reinforces the importance of education, harm reduction, treatment access, and stronger community partnerships. Whether through Narcan distribution, prevention programs, behavioral health support, or coordinated response efforts, every piece of the puzzle matters.
Awareness saves lives. Conversation saves lives. Action saves lives.
What more can we do as a community to respond to this growing threat?
Ohio has recorded the highest number of nitazene-related overdose deaths in the U.S. since 2021, according to the CDC.