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Presented today at   from JAMA:πŸ“Š Research Summary: In persistent   with significant low-voltage zones, adjunctive low-vo...
08/30/2026

Presented today at from JAMA:

πŸ“Š Research Summary: In persistent with significant low-voltage zones, adjunctive low-voltage zone ablation improved rhythm outcomes and health-related quality of life without increasing serious adverse events.

https://ja.ma/3V2aunA

Presented today at   from JAMA:πŸ’¬ Editorial by Peter Kistler, MBBS, PhD, and David Chieng, MBBS, PhD: In persistent  , re...
08/30/2026

Presented today at from JAMA:

πŸ’¬ Editorial by Peter Kistler, MBBS, PhD, and David Chieng, MBBS, PhD: In persistent , recent randomized trials continue to support pulmonary vein isolation as the procedural foundation, while adjunctive ablation beyond the pulmonary veins remains unsettled.

Pulsed field ablation-based posterior wall isolation did not significantly reduce the primary recurrence end point, although lower atrial arrhythmia burden suggests that the choice of end point may influence how benefit is assessed.

https://ja.ma/4zNC7Rc

Presented today at   from JAMA:Meta-a**lysis: In patients with   amyloid  , transthyretin  -silencing therapy reduced th...
08/30/2026

Presented today at from JAMA:

Meta-a**lysis: In patients with amyloid , transthyretin -silencing therapy reduced the composite of all-cause mortality and recurrent cardiovascular events vs placebo.

Treatment also reduced all-cause and preserved functional capacity and health status, supporting transthyretin suppression as a disease-modifying strategy.

https://ja.ma/4y9NsJO

Presented at   from JAMA:Among patients aged 65 to 80 years undergoing   for severe aortic valve stenosis, monotherapy w...
08/30/2026

Presented at from JAMA:

Among patients aged 65 to 80 years undergoing for severe aortic valve stenosis, monotherapy with a factor Xa inhibitor non–vitamin K antagonist oral anticoagulant reduced hypoattenuated leaflet thickening on 4-dimensional cardiac computed tomography vs acetylsalicylic acid monotherapy.

These findings suggest that anticoagulation may improve prevention of subclinical leaflet thrombosis after transcatheter aortic valve implant in selected patients.

https://ja.ma/4clDJrr

How does atrial fibrillation evolve across the metabolic and life course spectrum?Join Kirsten Bibbins-Domingo, PhD, MD,...
08/30/2026

How does atrial fibrillation evolve across the metabolic and life course spectrum?

Join Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA and the JAMA Network, and Barbara Casadei, MD, DPhil, Editor in Chief of JAMA Cardiology, for the joint session β€œAtrial Fibrillation Across the Metabolic and Life Course Spectrum.”

πŸ“ ESC Congress 2026
πŸ“… Sunday, August 30
πŸ•š 11:00 AM-12:00 PM

πŸ“£ Presented today at   from JAMA, JAMA Cardiology, and JAMA Network Open:➑️ From JAMA:Among patients with acute   treate...
08/29/2026

πŸ“£ Presented today at from JAMA, JAMA Cardiology, and JAMA Network Open:

➑️ From JAMA:

Among patients with acute treated with percutaneous coronary intervention, evolocumab before the procedure did not reduce all-cause death or unplanned cardiovascular hospitalization at 1 year vs standard care.
πŸ”— Read the study: https://ja.ma/3SC0YGY
πŸ’¬ Read the editorial by Kausik Ray, MD, and Christophe A. T. Stevens, PhD: https://ja.ma/4xxZtZK
πŸ“Š Read the research summary: https://ja.ma/4xyHXES

For persistent , pulsed field ablation with posterior wall isolation plus pulmonary vein isolation did not significantly reduce atrial tachyarrhythmia recurrence vs pulmonary vein isolation alone.
πŸ”— Read the study: https://ja.ma/4ckD7m1
πŸ“Š Read the research summary: https://ja.ma/3UeZ3sF

Among adults with established or high cardiovascular risk and recent nonadherence, digital outreach improved 14-day statin refill vs usual communication.
πŸ”— Read the study: https://ja.ma/4qKQF05
πŸ’¬ Read the editorial by Luke Laffin, MD: https://ja.ma/4i2sCYg
πŸ“Š Read the research summary: https://ja.ma/4gGiWA8

➑️ From JAMA Cardiology:

In patients with , a causal endotype-based classification identified distinct cardiac/coronary, cardiac/noncoronary, systemic, and indeterminate groups with different clinical profiles and 1-year outcomes.
πŸ”— Read the study: https://ja.ma/3SFFIQF
πŸ’¬ Read the editorial by Gjin Ndrepepa, MD, and Adnan Kastrati, MD: https://ja.ma/3SzTgxg

➑️ From JAMA Network Open:

Among 412 947 elective ablation procedures in Japan, in-hospital mortality was 0.029% and remained low during a decade of rapid growth in procedural volume and the number of hospitals performing ablation.
πŸ”— Read the study: https://ja.ma/4A3lfq7

🩺 In this nationwide study from Japan, elective   ablation was associated with low in-hospital mortality despite rapid g...
08/29/2026

🩺 In this nationwide study from Japan, elective ablation was associated with low in-hospital mortality despite rapid growth in procedural volume and the number of hospitals performing the procedure. Mortality remained low over time and declined modestly during the study period, with no evidence of a diffusion-related safety penalty. These findings indicate that expansion of elective ablation did not compromise procedural safety in routine practice.

https://ja.ma/4xwBRF2

Among women with their first delivery, obstetric a**l sphincter injury was associated with several nonmodifiable risk fa...
08/25/2026

Among women with their first delivery, obstetric a**l sphincter injury was associated with several nonmodifiable risk factors, highlighting that Cesarean delivery on maternal request is the only known, universally effective preventive strategy. https://ja.ma/4iu1PEc

Among commercially insured patients in Rhode Island, vertical integration and professional fees for hospital-affiliated ...
08/25/2026

Among commercially insured patients in Rhode Island, vertical integration and professional fees for hospital-affiliated clinicians increased more slowly than in neighboring states, suggesting Rhode Island’s Affordability Standards limit price increases. https://ja.ma/4xWJSTb

Among 2600 older women, earlier menopause was associated with faster white matter lesion accumulation decades after the ...
08/25/2026

Among 2600 older women, earlier menopause was associated with faster white matter lesion accumulation decades after the menopause transition, suggesting menopausing timing is a midlife marker for late-life dementia risk. https://ja.ma/4zSxANI

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