TargetCancer Foundation

TargetCancer Foundation TargetCancer Foundation (TCF) works to advance the development of more effective & personalized treatments for people with rare cancers.

We envision a world in which everyone diagnosed with a rare cancer has effective treatment options & a chance to live. The history of TargetCancer Foundation

TCF was founded in 2009 by Paul Poth, a dedicated husband, new dad, and lawyer with a passion for public service. Paul was diagnosed at the age of 38 with cholangiocarcinoma, a rare cancer that had no treatment or cure and very little resear

ch dedicated to it. For Paul, as for so many others fighting rare cancers, the diagnosis meant a best-guess treatment approach that relied on protocols developed for other cancers — all debilitating but none effective. Paul set out to speed research and innovation, determined to use whatever time he had to drive better outcomes for people with rare cancers like his. In his final months, while undergoing difficult treatments and parenting his son, Paul started TargetCancer Foundation and raised funds for our first research investment – $7,500 to the Center for Molecular Therapeutics at Massachusetts General Hospital. Paul died in August 2009, but the spark he lit has continued to grow. What began as an effort to fund basic research in rare cancers like cholangiocarcinoma and esophageal cancer has evolved into an organization that tackles challenges shared across all rare cancers, offering new options and support for everyone living with a rare cancer. Progress towards more effective and personalized treatments for rare cancers thrives when we work together. Whether you are a patient, caregiver, family member, friend, advocate, or supporter, there are many ways to get involved with TargetCancer Foundation. If you would like to get involved, please contact us.

We are honored to welcome Dr. Eileen O'Reilly of Memorial Sloan Kettering Cancer Center as our Scientific Keynote Speake...
09/01/2026

We are honored to welcome Dr. Eileen O'Reilly of Memorial Sloan Kettering Cancer Center as our Scientific Keynote Speaker at the 5th Annual Think Tank on Advancing Precision Medicine in Rare Cancers.

Dr. O'Reilly will present on: "The RAS Paradigm Shift in the Treatment of Pancreas Cancer and RAS-Driven Rare Cancers".

Join us in Boston on November 12th to learn how novel targeted strategies, such as daraxonrasib, are advancing clinical care and reshaping treatment options for patients with .

Register at www.targetcancer.org/thinktank

Present your rare cancer research to some of the field's leading experts.We're currently accepting abstracts for the 202...
08/27/2026

Present your rare cancer research to some of the field's leading experts.

We're currently accepting abstracts for the 2026 Think Tank on Advancing Precision Medicine in Rare Cancers, taking place in Boston on November 12th.

Early career investigators within 5 years of fellowship or a terminal degree are invited to submit and compete for up to $4,000 through the Evan Schumacher Fund Early Investigator Award.

Submission deadline: Monday, September 14, 2026

Learn more and submit your abstract: targetcancer.org/thinktank

Have you ever wondered what takes place in a Virtual Molecular Tumor Board (VMTB) meeting?In this presentation from the ...
08/25/2026

Have you ever wondered what takes place in a Virtual Molecular Tumor Board (VMTB) meeting?

In this presentation from the 2025 Think Tank on Advancing Precision Medicine in Rare Cancers, members of the TCF-001 TRACK VMTB present a case study on Prostatic Urethral Cancer.

Watch to learn how biomarker testing and multi-disciplinary expertise come together to uncover treatment options for difficult-to-treat rare cancers:

https://targetcancer.short.gy/RCTT-2025-MTB2

Do you want to see a TCF-001 TRACK VMTB session in person? Registration for is open! Visit targetcancer.org/thinktank

08/21/2026

What happens after biomarker testing?

On September 14th, our friends at Cancer Precision Medicine Commons will be hosting a webinar focused on navigating what comes next. They’ll share valuable resources to help patients and caregivers understand test results, access care, navigate insurance coverage, manage finances, and find support.

Register for the final session of their webinar series using the link below.

Registration is now open for the 5th Annual Think Tank on Advancing Precision Medicine in Rare Cancers!This highly inter...
08/20/2026

Registration is now open for the 5th Annual Think Tank on Advancing Precision Medicine in Rare Cancers!

This highly interactive, one-day scientific meeting unites leading researchers, clinicians, industry innovators, patients, advocates, and regulators to address one of oncology's greatest challenges: accelerating progress for patients living with rare cancers.

Join us in Boston on November 12 to connect with leaders at the forefront of rare cancer research and treatment and explore how scientific collaboration is reshaping precision medicine.

Learn more and register: www.targetcancer.org/thinktank

All of us at TCF were truly saddened to learn of the loss of Sydney Towle. Diagnosed with cholangiocarcioma at 23 years ...
08/07/2026

All of us at TCF were truly saddened to learn of the loss of Sydney Towle.

Diagnosed with cholangiocarcioma at 23 years old, she devoted herself to raising awareness of the experience of a young person living with a rare cancer, as well as the need for research funding for these cancers.

We are grateful to her for using her voice to so passionately and effectively elevate the needs of the rare cancer community and we send our deepest condolences to her family and friends.

For an audience that grew to more than a million followers, she challenged assumptions about how people with serious illnesses should look and live.

On September 16th, TCF President Kristen Palma will join Pickles Group Chief Clinical Officer, Kelsey Mora, LCPC, CCLS, ...
08/04/2026

On September 16th, TCF President Kristen Palma will join Pickles Group Chief Clinical Officer, Kelsey Mora, LCPC, CCLS, and Patient Advocate Eric Soares for a conversation focused on the unique experiences of families navigating a rare cancer diagnosis.

To join us, use the registration link below:

Rare cancers may be uncommon individually, but together they account for nearly 1 in 4 cancer diagnoses.

We're honored to be bringing together leading advocacy organizations, healthcare experts, and parents with lived experience for a free live webinar focused on the unique challenges of navigating a rare cancer diagnosis while raising children.

Join us for an honest conversation about talking to kids, supporting their emotional wellbeing, and finding connection through the uncertainty.

Registration is now open. Save your spot: https://forms.monday.com/forms/18bf7c299f962abc9006cf1b27269309?r=use1

Are you an early career investigator studying rare cancers?Abstract submissions are now open for TargetCancer Foundation...
07/30/2026

Are you an early career investigator studying rare cancers?

Abstract submissions are now open for TargetCancer Foundation's 2026 Think Tank on Advancing Precision Medicine in Rare Cancers taking place in Boston on November 12th.

Researchers within 5 years of fellowship or a terminal degree can submit for a chance to present to leading rare cancer experts and compete for up to $4,000 through the Evan Schumacher Fund Early Career Investigator Award.

Submission deadline: Monday, September 14, 2026

Learn more and submit your abstract: www.targetcancer.org/thinktank

New Blog Post!Navigating a Cancer of Unknown Primary (CUP) diagnosis comes with unique clinical and emotional challenges...
07/24/2026

New Blog Post!

Navigating a Cancer of Unknown Primary (CUP) diagnosis comes with unique clinical and emotional challenges.

In our latest post, TCF Clinical Research Manager Daniella Olonilua recaps key takeaways from our patient empowerment webinar, Coping with CUP: Navigating the Unknown, featuring Dr. Ryan Huey, Patient Advocate Tanya Knott, and TCF's Hetal Vig.

🔗 Read the OnTarget Rare Cancer Blog: https://targetcancer.short.gy/cupwb2

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