09/25/2026
Research Opportunity: NIH Study on Premature Ovarian Insufficiency (Ages 11–19)
The National Institute of Child Health and Human Development (NICHD) at the NIH is enrolling participants in a study of Premature Ovarian Insufficiency (POI).
POI occurs when the ovaries do not function normally at a young age, which lowers estrogen levels and can affect menstrual cycles, bone health, and overall well-being. POI is common in girls and women with classic galactosemia.
The study, led by Dr. Catherine Gordon, MD, MS, is looking at how hormone replacement therapy (HRT) with estrogen and progesterone affects the health of young people with POI.
Who may be eligible:
- Females ages 11–19
- Diagnosed with POI, or healthy volunteers with no known hormonal or other medical conditions
What the study involves:
- Clinic visits every 6 months for 2 years at the NIH Clinical Center in Bethesda, Maryland
- Visits may include a blood draw, occupational therapy, questionnaires, and imaging
To learn more or check eligibility, contact the NIH Clinical Center Office of Patient Recruitment and refer to Study #002141-CH:
- Phone: 877-888-3332 (TTY users dial 711)
- Email: [email protected]
- Online: go.nih.gov/002141CH
