Carmine Belin Lab

Hem
Sverige
Stockholm
Carmine Belin Lab

Ring Vägbeskrivning Webbplats Kontakta organisationen

Research laboratory at the Karolinska Institutet, Stockholm, focusing on neurological disorders like primary headache disorders.

The purpose of our research is to increase the understanding of the pathophysiology of neurological disorders with a focus on primary headache disorders such as migraine and cluster headache (CH) by identifying, characterizing and modelling genetic markers within the human genome. Certain rare forms of these conditions are monogenic and there is increasing evidence that genetic factors are important also for sporadic forms. We suggest that there are multiple genetic factors that combine in different ways to increase or decrease risk for disease. They need to be identified in order to begin unwinding the causative pathways leading to the different forms of the disorders. Knowledge about gene function and findings from linkage and genome-wide association studies are applied to clinical material (DNA and cell lines) collected from patients with migraine and CH as well as neurologically healthy controls to decipher genetic factors. Key genetic findings are evaluated by:

1. Quantification of possible candidate gene and protein expression differences caused by genetic variation in biological samples and in silico

2. Characterization of candidate gene and protein expression in human and rodent tissue

3. Development and characterization of transgenic animal models. The identification of new genetic risk and protective markers for these disorders should allow insight into the pathophysiological mechanisms, and thereby lead to improved diagnosis and aid in the development of novel classes of drugs able to prevent and/or counteract disease.

06/10/2026

Check out the activities at this years "Researchers’ Friday" which celebrated its 20th anniversary. Dr Joseph Lloyd from Centre for Cluster Headache talked about cluster headache to upper secondary school students🤩!

On 25 September, Researchers’ Friday (Forskarfredag) was held at Albanova University Centre and at several other locations across Sweden. This year, the event celebrated its 20th anniversary while also looking ahead to the discoveries and solutions that may shape the next 20 years. Under the theme...

24/09/2026

Time for KI Fun Run again with part of the team☀️! A lot of fun and well organized by 👏🏻👏🏻👏🏻!

16/09/2026

Check out interview with Dr Joseph Lloyd at the Centre for Cluster Headache featuring our article "Increased markers of heavy metal exposure and DNA methylation in cluster headache” the Cephalalgia Editor's Choice - August 2026!

Professor Simona Sacco, Cephalalgia Editor-in-Chief - Editor's Choi...

07/09/2026

Congratulations to Dr Felicia Jennysdotter Olofsgård at the Centre for Cluster Headache who has been awarded with the International Headache Society Junior Research Grant to study the biological mechanisms underlying cluster headache🙌. The project will examine how genetic variants associated with the condition affect immune cells and may contribute to disease development.

The International Headache Society has awarded Felicia Jennysdotter Olofsgård a Junior Research Grant to study the biological mechanisms underlying cluster headache. The project will examine how genetic variants associated with the condition affect immune cells and may contribute to disease develop...

03/08/2026

Kolla in möjlighet att delta i ny studie med yogabaserade kroppsövningar vid huvudvärk:

Har du diagnostiserad primär huvudvärk som högfrekvent migrän och/eller klusterhuvudvärk? Forskare söker dig som vill testa om yogabaserade kroppsövningar kan hjälpa dig att förbättra din hälsa genom vägledd webbaserad digifysisk träning jämfört med att inte träna. Studien genomförs...

25/06/2026

Deltagare till studie med yogabaserade kroppsövningar vid huvudvärk sökes!

03/06/2026

Det finns fortfarande chans att delta i en studie om tobakskonsutmtion och klusterhuvudvärk!
https://redcap.ki.se/surveys/?s=XCHDN38RTRDLCWAJ

Vill du delta i en studie om tobakskonsumtion och klusterhuvudvärk?

Vi söker studiedeltagare med och utan klusterhuvudvärk (Hortons huvudvärk) för att besvara en enkät om tobaksvanor samt ev. lämna ett urinprov. Använd följande länk för mer information och möjlighet att delta i studien:

https://redcap.ki.se/surveys/?s=XCHDN38RTRDLCWAJ

02/06/2026

Finally time for a lab spring workshop and afternoon retreat🛶💦!

08/05/2026

Part of Centre for Cluster Headache visited Neurologiveckan 2026 in sunny Jönköping where Dr Felicia Jennysdotter Olofsgård received her diploma for this year’s Pfizer and Svenska Huvudvärkssällskapet / Swedish Headache Society scholarship for research on migraine and other primary headache disorders 2026🤩!

14/04/2026

Excited to see our work on molecular clock dysfunction and cluster headache at the Centre for Cluster Headache published in Cephalalgia! Thank you all co-authors for a great collaboration!

Background / Hypothesis Headache attacks are reported to occur with circadian rhythmicity by 2/3 of individuals with cluster headache, hinting to potential dysf...

Adress

Solnavägen 9
Stockholm
17177

Telefon

+46852487051

Webbplats

http://ki.se/en/neuro/carmine-belin-laboratory

Aviseringar

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