Vitamin K has been known as the coagulation vitamin, because of its role in the blood-clotting process. However, research over the last few decades has shown that the role of K Vitamins – and Vitamin K2, the menaquinones, in particular – has been greatly expanded. Of note, K Vitamins activity outside the liver is required for calcium utilization, the key factor in maintaining both bone and cardiov
ascular health. Vitamin K2 helps to activate vitamin K-dependent proteins responsible for healthy tissues. In bone, it activates osteocalcin, a protein required to bind calcium to the mineral matrix, thus strengthening the skeleton. In circulation, Vitamin K2 participates in carboxylation of Matrix Gla Protein (MGP), the most potent inhibitor of arterial calcification known, lowering the risk of vascular damage. As the scope of research expands other new functions, crucial to our wellbeing, are now emerging. The latest studies have not only confirmed Vitamin K2’s positive function towards osteoporosis and cardiovascular diseases, but also revealed new and exciting applications, including the activity of vitamin K and Alzheimer's disease, a variety of cancers, the incidence and severity of varicose veins, skin aging and others.
