01/06/2026
CEPI is urgently accelerating the development of three investigational vaccine candidates towards clinical trials in response to the deeply concerning Bundibugyo ebolavirus epidemic.
The outbreak, affecting the Democratic Republic of the Congo and Uganda, has been classified as a public health emergency by both the Africa CDC and the World Health Organization (WHO). Just weeks since it was declared, it is already the third-largest Filovirus outbreak in history.
With no licensed vaccines available for Bundibugyo virus and none in clinical development, CEPI's action reflects the critical need to produce additional tools to help curtail the outbreak.
CEPI is investing up to $62 million to back a portfolio of candidates under development from longstanding partners with proven capabilities. These include candidates developed by IAVI, Moderna, and the University of Oxford, which will be manufactured at the Serum Institute of India Pvt. Ltd.
The candidates were selected based on CEPI's comprehensive global review of Bundibugyo virus vaccines in development and extensive consultation with WHO, Africa CDC, ANRS-MIE, Gavi, the Vaccine Alliance and affected countries. Each uses a different validated vaccine technology to maximise the likelihood of success.
All of the underlying vaccine technology platforms—rVSV, mRNA and ChAdOx1—have extensive safety data and have been used to develop vaccine candidates that have shown preclinical or clinical efficacy against related filoviruses.
CEPI’s funding will ultimately support each vaccine candidate to begin clinical trials as quickly as possible.
➡️ Get the details in the press release: https://cepi.net/cepi-fast-tracks-three-bundibugyo-ebolavirus-vaccine-candidates
➡️ CEPI has also opened an urgent Call for Proposal seeking additional Bundibugyo virus vaccine candidates. Learn more and apply here: https://cepi.my.site.com/call-for-proposal?id=a1zP3000008XbgvIAC