Attività di Ricerca
La Fondazione, a seguito di un accordo di collaborazione con il Consorzio C.A.R.S.O., sito nel Campus, utilizza le infrastrutture e le apparecchiature scientifiche del Consorzio. Svolge attività di ricerca nel campo delle omiche per la Medicina di Precisione e per la Terapia Personalizzata nel campo delle malattie renali
L’attività di ricerca è documentata dalle seguenti pubbli
cazioni:
Lavori originali
Sallustio F, Costantino V, Cox SN, Loverre A, Divella C, Rizzi M, Schena FP. Human renal stem/progenitor cells repair tubular epithelial cell injury through TLR2-driven inhibin-A and microvescicle-shuttled decorin. Kidney Int. 83: 392-403, 2013. (I.F. 7.916)
Sallustio F, Serino G, Costantino V, Curci C, Cox SN, De Palma G, Schena FP. miR-1915 and miR-1225-5p regulate the expression of CD133, PAX2 and TLR2 in adult renal progenitor cells. PLoS One. 8: e68296, 2013. (I.F. 3.730)
Sallustio F, Cox SN, Serino G, Curci C, Pesce F, De Palma G, Papagianni A, Kirmizis D, Falchi M, Schena FP. Genome-wide scan identifies a copy number variable region at 3p21.1 that influences the TLR9 expression levels in IgA nephropathy patients. Eur J Hum Genet. 23: 940-8, 2014. (I.F. 4.225)
Serino G, Sallustio F, Curci C, Cox SN, Pesce F, De Palma G, Schena FP. Role of let-7b in the regulation of N-acetylgalactosaminyltransferase 2 in IgA nephropathy. Nephrol Dial Transplant. 30:1132-9, 2015. (I.F. 3.488)
Cox SN, Serino G, Sallustio F, Blasi A, Rossini M, Pesce F, Schena FP. Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients. Nephrol Dial Transplant. 2015 Mar 13. pii: gfv017. [Epub ahead of print] PubMed PMID: 25770168. (I.F. 3.488)
Pesce F; Diciolla M; Binetti G; Naso D; Ostuni VC; Di Noia T; Vagane AM; Bjorneklett R; Suzuki H; Tomino Y; Di Sciascio E; Schena FP. Clinical decision support system for end-stage kidney disease risk estimation in IgA nephropathy patients. Nephrol Dial Transplant 31: 80-6, 2015 (I.F. 3.488)
Serino G, Pesce F, Sallustio F, De Palma G, Cox SN, Curci C, Zaza G, Lai KN, Leung JC, Tang SC, Papagianni A, Stangou M, Goumenos D, Gerolymos M, Takahashi K, Yuzawa Y, Maruyama S, Imai E, Schena FP. In a retrospective international study, circulating miR-148b and let-7b were found to be serum markers for detecting primary IgA nephropathy. Kidney Int. 2015 Nov 18. doi: 10.1038/ki.2015.333. (I.F. 8.563)
Sallustio F, Serino G, Cox SN, Dalla Gassa A, Curci C, De Palma G, Banelli B, Zaza G, Romani M, Schena FP. Aberrantly Methylated DNA Regions Lead to Low Activation of CD4+ T Cells in IgA Nephropathy. Clin Sci (Lond). 2016,130: 735-748 (I.F. 5.598)
Review
Schena FP, Serino G, Sallustio F. MicroRNAs in kidney diseases: new promising biomarkers for diagnosis and monitoring. Nephrol Dial Transplant. 29: 755-63, 2014. (I.F. ). Biomarkers and personalized therapy in chronic kidney diseases. Expert Opin Investig Drugs. 23:1051-4, 2014(I.F. ). Schena FP., Sallustio F. and Serino G. microRNAs in glomerular diseases from pathophysiology to potential treatment target. Clinical Science 128: 775–788, 2015 (Printed in Great Britain). (I.F.5.598). Sallustio F., Serino G., and Schena FP. Potential Reparative Role of Resident Adult Renal Stem/Progenitor Cells in Acute Kidney Injury. BioResearch Open Access, Volume 4.1, 2015 (I.F. N/A)
Serino G, Curci C, Schena FP. Role of miR-422a and kallikrein-related peptidase 4 implicated in the development of lupus nephritis. Do we work in this direction? Nephrol Dial Transplant. 2015 Nov 27. pii: gfv396 (I.F.3.577). Comitato Scientifico
Il Comitato Scientifico è costituito da illustri ricercatori europei nel campo delle malattie renali ed è coordinato dal Presidente della Fondazione.
