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Cancer Trials Ireland

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Cancer Trials Ireland

Cancer Trials Ireland is a not for profit Clinical Research Organisation.

Our vision is for patients with cancer to have the opportunity to participate in potentially life enhancing cancer trials in Ireland.

31/08/2026

Cancer Trials Ireland Clinical Lead Prof Seamus O’Reilly and CEO Angela Clayton-Lea attended the first meeting of CTAC Ireland last week, as the new Clinical Trials Advisory Council begins its work.

The Council has been established to implement the recommendations of the National Clinical Trials Oversight Group and support the development of a more streamlined, coordinated and internationally competitive clinical trials environment in Ireland.

As the national cancer trials network, Cancer Trials Ireland welcomes the opportunity to contribute directly to this work, bringing our experience of developing, opening and sponsoring cancer trials across Ireland and our focus on improving access to trials for patients.

CTAC Ireland is chaired by Prof Donal Brennan and supported by a Secretariat led by Dr John O Neill in the Department of Health’s Research Policy and Innovation Unit.

The Council brings together expertise from across Ireland’s health research ecosystem, with an important opportunity to deliver meaningful improvements for clinical trials and, ultimately, for patients in Ireland.

Read more: https://bit.ly/4xw79fa

29/08/2026

What an amazing day at The Curragh Racecourse for the Pat Smullen Race Day. 💙

We’re once again in awe of the support from the racing community for Cancer Trials Ireland and the incredible legacy Pat created.

A huge thank you to the Smullen family, everyone who took part in the Curragh to Curragh Charity Cycle, the riders, organisers, sponsors, volunteers and everyone who supported the day.

Pat was a remarkable man, and it’s very special to see so many people continue to come together in his name.

20/08/2026

A major breakthrough in metastatic pancreatic cancer is showing what new treatment options can achieve.

Daraxonrasib, an investigational oral RAS inhibitor, has nearly doubled overall survival compared with standard chemotherapy in patients with previously treated metastatic pancreatic cancer.

For Cancer Trials Ireland, this also reinforces the importance of being able to open and deliver pancreatic cancer trials in Ireland.

Since 2019, support from the Pat Smullen Fund has enabled Cancer Trials Ireland to open four clinical trials for people with pancreatic cancer, helping patients access treatment options that may otherwise not have been available to them.

The Pat Smullen Race Day has played an important part in that support over the past seven years.

This year’s Race Day takes place at the Curragh on Saturday, 29 August. By buying a ticket and supporting the day, you are helping us continue to open more trials and improve access to new treatment options for people with pancreatic cancer in Ireland.

🎟️ Tickets: https://bit.ly/4zpz9lR

19/08/2026

A great milestone for ENGOT cx22 Trofuse-036, which is now open and recruiting at Mater Misericordiae University Hospital, Cork University Hospital and St James’s Hospital.

Congratulations to NLI Prof Dearbhaile Collins, study sponsor ENGOT, and the clinical trials teams across all three sites.

Special congratulations to the team at Mater Misericordiae University Hospital, where the first patient in Ireland has now been enrolled on the study.

The trial is for people with metastatic cervical cancer and is investigating sacituzumab tirumotecan (sac-TMT) and pembrolizumab, with or without bevacizumab, compared with standard treatment.

Find out more: https://bit.ly/4wxZDio

14/08/2026

We were proud to see the results of the ground-breaking PRO-ACT study receive national attention yesterday, shining a light on an issue that too often goes unspoken after prostate cancer treatment.

PRO-ACT is a Cancer Trials Ireland patient-led study, reflecting our commitment to research shaped and led by patients and focused on the questions and experiences that matter most to them.

Led by co-Chief Investigators Martin Sweeney and Professor Paul Kelly, the study found that two-thirds of patients surveyed were either underprepared or completely unprepared for the impact treatment would have on their sexual function.

Martin joined Dr Claire Kilty, Head of Research at the Irish Cancer Society , on Today with David McCullagh on RTÉ Radio 1 to discuss the findings. PRO-ACT also featured on RTÉ television news and in the Irish Examiner .

The study was funded by the Irish Cancer Society, with additional support from Black Raven Credit Union Limited
Men Against Cancer (now Prostate Cancer Ireland ), The Hospital Saturday Fund and Friends of Cancer Trials Ireland.

Thank you to the patients and partners who shared their experiences and made this research possible.

🎧 Listen back: https://bit.ly/4wSS7zE
📰 Read the Irish Examiner coverage: https://bit.ly/4cFwf2x

13/08/2026

We’ve been very encouraged by the response to Cancer Trials Ireland’s Pre-Budget Submission for Budget 2027.

Thank you to everyone who has reached out to discuss our proposals, and to those who have invited us to meet and talk through what greater investment in cancer trials could deliver for patients and for Ireland.

Our submission makes three targeted asks:

1️⃣ Create a €250,000 seed fund to support Cancer Trials Ireland and trial sites nationally to begin implementing the recommendations of the National Clinical Trials Oversight Group, through collaboration with the Clinical Trials Advisory Council.

2️⃣ Fund a critical Site Set-Up Specialist role to help improve trial start-up times in Ireland, supporting sites to accelerate study activation and patient recruitment.

3️⃣ Create a national “Optimisation Trials” fund, supporting trials that investigate whether existing cancer treatments can safely be given at a lower dose, less often or for a shorter period, reducing treatment burden for patients and potentially delivering significant savings to the State.

Together, these proposals represent a targeted investment in patient access, a stronger cancer trials environment and Ireland’s competitiveness as a location for high-trust, high-quality clinical trials.

Our full Pre-Budget Submission is available to read on our website: https://bit.ly/3SuIkkn

If you have questions about any of our proposals, or would like to meet with Cancer Trials Ireland to discuss them, we would be very happy to hear from you.

11/08/2026

📢 Funding opportunity for clinical researchers

Our funders, the Irish Cancer Society , are currently accepting applications for the Cancer Clinical Study Seed Award 2026, supporting non-regulated interventional clinical studies.

💶 Up to €100,000 in funding
📅 Funding period: 12–60 months
🏆 Two awards available
⏰ Deadline: Wednesday, 23 September 2026

Cancer Trials Ireland can support applications where appropriate and can act as the host institution for the grant.

Applicants are also encouraged to engage with Cancer Trials Ireland early in the application process, including for advice on patient involvement in clinical trials.

Find out more about the award, eligibility and application process:
https://bit.ly/4xv0xwY

07/08/2026

Did you know? All of the videos from Cancer Retreat 2026 are now available to watch on our YouTube channel.

The playlist includes presentations and discussions on optimisation trials, investigator-initiated research, patient involvement, funding, trial start-up and international collaboration.

Watch the full playlist:
https://bit.ly/4vN9oZD

05/08/2026

Meet the Team: Kate Hatton💙

Kate joined Cancer Trials Ireland in 2021 as a Clinical Trial Assistant (CTA) and is now a Senior Clinical Research Associate (CRA), working across a range of clinical studies.

On a day-to-day basis, Kate's key responsibility is visiting hospitals running our clinical trials. From initiation visits and training site staff on study procedures to monitoring visits throughout the trial, she helps ensure each study is conducted to the highest standard. As a CRA, Kate reviews many aspects of a trial—including protocol compliance, high-quality data collection, and patient safety—to help ensure the results can contribute to developing better treatments for patients.

Kate's role is an important link between hospital sites and Cancer Trials Ireland throughout the life of a study. Site staff can reach out to their CRA with any questions or concerns, and this close collaboration helps teams carry out clinical trial activities with confidence.

What Kate loves most about working at Cancer Trials Ireland is the supportive team. "Everyone is always willing to help, no matter how busy they are." She also finds it incredibly rewarding to hear from site staff that patients are benefiting from the clinical trials she's working on.

04/08/2026

The DP-IMRT Pancreas Study has progressed to Phase II following the completion of Phase I.

Eleven patients were enrolled in Phase I, which established the optimum radiotherapy dose for the next stage of the study. Phase II is now open at Saint Luke's Radiation Oncology Network and St. Vincent's University Hospital and planned to open at Beacon Hospital. 49 patients will be enrolled for Phase II.

The study is led by Chief Investigator Dr Gerard McVey and Co-Chief Investigator Dr Maeve Keys, both at Saint Luke's Radiation Oncology Network.

Congratulations to the study team, teams at SLRON and SVUH, our colleagues at Irish Research Radiation Oncology Group (IRROG) and everyone involved in reaching this next phase 👏

Find out more: https://bit.ly/4xcJtMg

Address

RCSI House, 121 Street Stephen's Green
Dublin

Opening Hours

Monday	9am - 5pm
Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm
Friday	9am - 5pm

Telephone

+35316677211

Website

http://www.cancertrials.ie/

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