09/10/2026
This World Mental Health Day, we're recognising the importance of mental health for people living with cystic fibrosis (CF) and the need for research and care to evolve alongside the changing experience of the condition.
CF has changed. Our approach to mental health needs to change with it.
For people living with cystic fibrosis, the mental health burden can be significant. CF brings a demanding daily treatment regimen, uncertainty, hospitalisations, pain, social isolation and the challenge of navigating relationships, work, family and life alongside a lifelong condition.
And now, in the era of CFTR modulators, there is another dimension to understand.
For many people, modulators have brought remarkable improvements in health, wellbeing and hope. But emerging research indicates that a smaller group experience new or worsening symptoms after starting treatment, including anxiety, depression, irritability, sleep disturbance or cognitive symptoms. The reasons are not yet understood and require further research.
This isn't about questioning the enormous benefits of CFTR modulators.
It's about making sure we understand the whole experience of living with CF.
The latest psychosocial research identifies understanding the neuropsychiatric effects of CFTR modulators, improving screening, and developing better psychosocial support as important priorities for CF research and care.
At Cure4CF, we believe research needs to keep pace with the changing reality of CF.
Because better CF care isn't only about lung function.
It's about helping people live longer — and live well.
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🧡 If you need support:
Living with CF can be challenging, and it's okay to ask for help. If you're struggling with your mental health, please speak with your CF care team, GP or a mental health professional.
You can also contact Lifeline on 13 11 14 or Beyond Blue on 1300 22 4636 for support.
