Project ALS

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Project ALS Project ALS is finding and funding a cure for ALS. Learn more at projectals.org.
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ALS needs the best minds, wherever they begin. At Project ALS we don’t just look for the best ALS researchers. We look f...
10/09/2026

ALS needs the best minds, wherever they begin.

At Project ALS we don’t just look for the best ALS researchers. We look for the best researchers, period.

For nearly three decades, we’ve actively recruited scientists from outside the traditional ALS field, bringing new expertise, technologies, and ways of thinking to the problems ALS research needs to solve.

Dr. Elizabeth Engle studies the motor neurons that control eye movement, neurons that are remarkably resistant to ALS. We brought her expertise into ALS to ask: What can the motor neurons ALS spares teach us about protecting the ones it attacks?

Dr. Talmo Pereira pioneered the use of AI to capture and analyze movement from video. We brought his expertise into ALS to ask: Can AI detect changes in movement that humans can’t see, helping us recognize ALS earlier and measure disease more precisely?

Dr. Ai Yamamoto studies how brain cells identify and clear damaged or abnormal proteins. We recruited her to ask: Why can't ALS motor neurons clear these harmful proteins, and could correcting defects in the cellular recycling system help motor neurons survive?

Different fields. Different expertise. One very difficult problem.

Sometimes the person with the next great insight into ALS hasn’t spent their career studying ALS.

Our job is to find them, bring them into ALS, and give them the resources to get to work.

Happy DAF Day! What will your DAF do?🎉🧡A Donor-Advised Fund (DAF) is more than a way to give. It’s an opportunity to tur...
10/08/2026

Happy DAF Day! What will your DAF do?🎉🧡

A Donor-Advised Fund (DAF) is more than a way to give. It’s an opportunity to turn your charitable dollars into meaningful impact. By recommending a grant to Project ALS through your DAF, you can help fuel innovative ALS research.

This DAF Day, we would appreciate it if you put your generosity to work for science! 🔬
Learn how to support Project ALS through your Donor-Advised Fund: https://bit.ly/4jGcc8A

10/07/2026

Meet Andrew. He’s no stranger to going the distance for ALS. After taking on the Los Angeles Marathon with , Andrew is back for another marathon, this time through the streets of New York City.

He is running in honor of his brother, Joey, who is living with ALS. Every mile is personal, and every step reflects his commitment to supporting the research working toward a cure.

Support Andrew as he races forward and advances ALS research. Donate to Andrew’s run: https://bit.ly/3UbWOqc 📢

This week we celebrate DAF Day! A donor-advised fund can make giving to charity simpler, more purposeful, and more effec...
10/05/2026

This week we celebrate DAF Day!

A donor-advised fund can make giving to charity simpler, more purposeful, and more effective. If you already have a DAF or are thinking of setting one up, the money you donate can be used to support ALS research, which is helping us get closer to effective treatments and eventually a cure.

This DAF Day, put your giving to work for ALS research. Learn more about donor-advised giving and recommend a grant to Project ALS: projectals.org/dafgiving

10/04/2026

A message from Meredith Estess~

In 1998, when my and Valerie’s sister, Jenifer, was diagnosed with ALS at age 35, her doctor told her to max out her credit cards and go see the world. There was no medicine for her, and she was told she would die within the next two to five years.

Jenifer, Valerie, and I, along with an entire community of friends and loved ones, sought out the most promising research, but there wasn’t much to find. Jenifer was pretty sure that treatments or a cure would not come in time to save her. Even so, she found the disease and her prognosis unacceptable and wanted to make an impact on the patients who would come after her. We created Project ALS in 1998, out of love and with the determination to create a new paradigm for ALS research.

Project ALS has been finding and funding research for 28 years. We have moved the needle in ALS research forward because we are a unique organization unlike any other. Project ALS requires doctors and researchers to work together, share data, stick to deadlines, and report progress. We hold scientists accountable. These mission cornerstones move research forward faster.

It's that time of the year again! 🎁 This holiday season, enjoy purchasing some gifts that give back. Shop holiday statio...
10/03/2026

It's that time of the year again! 🎁 This holiday season, enjoy purchasing some gifts that give back. Shop holiday stationery and gifts from Minted and use code FUNDRAISEPROJECTALS to enjoy 20% off your purchase.

Minted will donate 10% to Project ALS, helping support the research that moves us closer to a future without ALS: https://bit.ly/4xY8Q4k

We ♥️ our Project ALS Family.Every research program has a community behind it. For more than 25 years, our community has...
10/02/2026

We ♥️ our Project ALS Family.

Every research program has a community behind it. For more than 25 years, our community has helped Project ALS find and fund promising research, bring scientists together, and give bold ideas the support they need to grow.

Behind every experiment and every question asked is a community that believes a future without ALS is possible and that encourages each other to keep going and fighting.

All of our discovery and work is possible because of you. 🫂

Help fuel research here: https://bit.ly/3W2ViXQ

Today, we are proud to share an important new chapter for Project ALS: the launch of our Emerging Leaders Board.For near...
10/02/2026

Today, we are proud to share an important new chapter for Project ALS: the launch of our Emerging Leaders Board.

For nearly three decades, Project ALS has been powered by a community committed to driving ALS research forward, faster. Now, we are expanding our leadership with a new generation of perspectives and networks to strengthen our mission, broaden our reach, and grow support for ALS research.

We are thrilled to welcome our 11 inaugural members, whose energy and commitment will help shape the future of Project ALS for years to come.

Learn more about the board here: https://bwnews.pr/4iVmYrh

Artificial Intelligence (AI) is a revolutionary technology, but can it cure life-threatening diseases like ALS? Promptin...
09/30/2026

Artificial Intelligence (AI) is a revolutionary technology, but can it cure life-threatening diseases like ALS? Prompting AI is a significant factor in its use, and here at Project ALS, we are asking AI two big questions:

1️⃣ Can those with the more common form of ALS, known as "sporadic," benefit from the powerful recent treatments developed for the rarer, or "familial," forms of ALS?
2️⃣ Can it help us diagnose ALS earlier and with greater accuracy?

Led by Drs. Steven Altschuler and Lani Wu at the University of California, San Francisco, in the Project ALS Therapeutics Core, are asking AI to determine whether a medicine developed for rare ALS may help more people living with ALS.

At the Salk Institute, Drs. Eiman Azim and Talmo Pereira are using everything from motor neuron biology and deep learning to drive earlier diagnosis. Their new "pose tracking" system is powered to identify the very first motor changes in ALS. Their prototype can also be used to test drugs for their effects on movement in ALS.

Fall is officially here, and so is your new favorite layer. 🍂 Make it clear how you feel about ALS while staying warm an...
09/28/2026

Fall is officially here, and so is your new favorite layer. 🍂

Make it clear how you feel about ALS while staying warm and dry in our new ALS Hater windbreakers. Great for crisp mornings and rainy days, these are made for those who aren't afraid to make a statement in rain, sleet, or snow.

Your purchase supports Project ALS research.

Available now in black and olive, shop the new ALS Hater windbreakers here: https://bit.ly/4rBOMmD

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