HDBuzz

Huntington's Disease research news. In plain language. Written by scientists. For the global HD community.

05/06/2026

Behind every HDBuzz article is a team of real people, scientists, writers, editors, who care deeply about making Huntington’s disease research clear, accurate, and accessible.

They’re not just reporting the science. They’re part of the community.

From translating complex studies into plain language, to double-checking every detail, their work helps keep everyone informed, connected, and empowered.

If HDBuzz has helped you understand HD just a little better, you’ve seen their impact. Please consider donating and sharing so we can continue to give you HD research news in plain language.

https://en.hdbuzz.net/donate/

05/04/2026

PTC Therapeutics has shared 2-year data on votoplam, a once-daily HTT-lowering pill. In Stage 2 participants, results suggest up to 52% slowing of disease progression.

This article goes through what the data show, what’s still unclear, and how the Phase 3 trial is taking shape.

https://en.hdbuzz.net/two-years-in-new-long-term-extension-data-from-pivot-hd-for-votoplam/

05/01/2026

Hey HD clinics — do your patients read HDBuzz?

We hear often that HDBuzz articles come up in clinic appointments — patients who've read our coverage, caregivers who come in with questions, staff who share our pieces in waiting rooms.

That's exactly what we're here for. And this week, we're asking clinics to help Fund the Buzz.

Share our posts. Tell your patients. Point someone to https://en.hdbuzz.net/donate/

The HD clinic community is some of our most loyal readers. Help us keep the lights on for everyone.

04/30/2026

April brought a clearer picture into focus: a toxic HTT fragment taking center stage in mouse research, CRISPR approaches continuing to show promise in early studies, AI and wearable tech moving closer to real-world clinical use, and new research highlighting the often unseen weight carried by HD caregivers.

Full Article: https://en.hdbuzz.net/april-2026-this-month-in-huntingtons-disease-research/

04/28/2026

345,000 unique visitors.
100 articles.
12 languages.

But behind every one of those numbers is a person, a caregiver at 2am trying to understand a trial result. A trial participant at a clinic appointment wanting to ask their doctor the right question. A family member who just got a diagnosis and doesn't know where to start.

HDBuzz exists for all of them. It always will, as long as our community makes it possible.

Fund The Buzz: https://en.hdbuzz.net/donate/

04/27/2026

To kick off Clinic Week during our Fund the Buzz spring fundraising campaign, we're publishing a piece that's been on a lot of people's minds lately: what is a TFC score, and why does it matter so much for the INVEST-HD trial?

If you or someone you love is wondering about votoplam eligibility, this one's for you.

Full article: https://en.hdbuzz.net/the-number-on-the-scale-what-the-tfc-score-measures-and-why-it-matters-right-now/

04/26/2026

This week is Fund the Buzz: HD Clinic Week (April 27–May 4) 🧠

If you work at an HD clinic, attend one, or support someone who does, this one's for you.

HD clinics are where science meets real life. They're where families get news, good and hard, and where HDBuzz articles get pulled up on phones for families to ask specific questions about HD research and clinical trial news.

We're asking HD clinics to help spread the word this week. Host something, share our posts, or just send a friend to https://en.hdbuzz.net/donate/
Every action counts.

Want to participate? Email [email protected], we'd love to celebrate your efforts.

04/24/2026

Here's some of what it actually costs to run an independent HD science newsroom:
🔹 Journalism insurance: ~$8,000/yr
🔹 Editorial support on pace with HD research: ~$24,000/yr
🔹 Website & infrastructure: ~$9,000/yr

Our spring goal is $30,000. That amount keeps HDBuzz independent, lawsuit-protected, and free for every HD family, wherever they are in the world.
Every dollar comes from readers like you. Zero from pharma.

Fund the Buzz: http://hdbuzz.net/donate

04/23/2026

Apathy in Huntington’s disease isn’t just “not caring.” It can reshape relationships, disrupt daily routines, and strain emotional connection in ways that are often misunderstood.

A small study of caregivers highlights just how heavy that toll can be, and how important it is to have safe spaces to share, connect, and be heard.

Full Article: https://en.hdbuzz.net/dancing-with-a-stranger-understanding-apathy-in-huntingtons-disease-through-caregivers/

If this article resonates with you, and you want to help keep content like this free and accessible to everyone, you can support us by sharing our page or donating on our website: http://hdbuzz.net/donate

04/22/2026

HDBuzz has never accepted money from pharmaceutical companies.

Not because we don't root for the drugs in the pipeline - we genuinely hope they’re all successful! But taking money from organizations with a financial stake in specific treatments would compromise the one thing that makes HDBuzz worth reading: **we have no dog in the fight.**

When our writers say a trial result is exciting, it's because the data is exciting. When they urge caution, it's because the data warrants it.

That independence is funded entirely by our community. Help us protect it: https://en.hdbuzz.net/donate

04/21/2026

HD science is moving fast. When the FDA made a controversial decision about the first HD gene therapy last fall, nearly 29,000 people read our coverage in the days that followed - about as many visitors as we normally see in an entire month.

People come to HDBuzz when it matters most. This week, we're launching Fund the Buzz, our spring fundraising campaign, and we're sharing exactly what it costs to keep this resource free for the HD community, including why journalism insurance is surprisingly important in HD research.

Read this article: https://en.hdbuzz.net/fund-the-buzz-the-8000-reason-hdbuzz-can-tell-you-the-truth/

donate: https://en.hdbuzz.net/donate/

and more on our website: https://en.hdbuzz.net/

04/20/2026

HDBuzz is launching Fund the Buzz, our spring fundraising campaign!

We’re proudly independent, free to read, and run by scientists who truly understand Huntington’s disease. That independence means everything, but it also means we rely on support from our community to keep going.

Help us keep the lights on (and stay lawsuit-free). Every share and donation makes a difference.

Full Article: https://en.hdbuzz.net/fund-the-buzz-the-8000-reason-hdbuzz-can-tell-you-the-truth/

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