Cure Gaba-A

Cure Gaba-A Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from Cure Gaba-A, Nonprofit Organization, 30765 Pacific Coast Highway Suite 366, Malibu, CA.

Our mission is to accelerate lifesaving treatments for GABAAR-related brain disorders by funding cutting-edge science, championing innovative therapies, and building a global network of researchers and patients.

02/28/2026

CURE GABA-A | Rare Disease Day

There are many events happening today on Rare Disease Day. If you’re attending one, please tag us!

Participate. Represent. Show your support. Wear your strips proudly!

We hope you enjoy the day with your little zebra!

Rare doesn’t mean invisible.
And our children cannot wait.
Learn more. Help us move treatments forward.

curegabaa.org

GABRA6 GABRB1 GABRB2 GABRB3 GABRG1 GABRG2 GABRG3 GABRR1 GABRR2 GABRR3 GABRE GABRD GABRQ GABRP

CUREGABAa.org/donate
02/23/2026

CUREGABAa.org/donate

02/22/2026

The Drug Exists. The Children Are Waiting.

Children with GABAAR genetic disorders suffer from severe epilepsy, developmental delay, loss of speech, loss of movement, and constant seizures. Many are losing skills every day.

But there is hope.
A potential therapy already exists and it is working in early research.

Now we must finish testing it so it can reach our children.

This video is part of the CURE GABA-A 2-2-2 Challenge:

Donate $2.22 • $22 • $222 • $2,222

We have already:

Developed the drug
Licensed genetically modified mouse models
Begun preclinical testing (as of 02.2026)

Now we need community support to complete testing and move toward FDA approval.

This is not hypothetical.
Children are waiting.
The science is real.
Time matters.

Donate here:
https://www.classy.org/campaign/cure-gaba-a-or-mrna-therapy/c559662

Learn more:
https://curegabaa.org

Please like, share, donate, and challenge others.
Together, we can turn research into treatment.

HopeForKids RareDiseaseAwareness GeneBasedTherapy

02/21/2026

CURE GABA-A | We Challenge You 🤍

Two dollars. Two minutes. Two friends.

1. Donate $2.22 • $22 • $222 • $2222
2. Make a video
3. Challenge 2 friends

Give children a chance at life.
A drug already exists.
We’re testing it now so children with severe epilepsy can access it.

What will YOU give up today to help keep epilepsy away?

🔗 Donate + learn more: https://www.classy.org/campaign/cure-gaba-a-or-mrna-therapy/c559662

CURE GABA-A New Publication Alert GABRB2 & GABRB3This publication exists because families shared their real-world experi...
01/28/2026

CURE GABA-A New Publication Alert GABRB2 & GABRB3

This publication exists because families shared their real-world experiences

Huge recognition to Dr. Sebastian Ortiz, Dr. Rikke S. Møller, and an incredible global team who studied 117 individuals with GABRB2 & GABRB3 variants, examining seizure onset, variant type, motor development, cognition, and outcomes.

Key findings:
• Gain-of-function variants → earlier seizure onset & greater motor challenges
• Earlier seizure onset predicts more severe motor outcomes
• Seizure onset can now guide early clinical decision-making

This is so important for our families and physicians it allows them to plan earlier therapies, mobility supports, and care before long-term outcomes are known.

Many families in our community contributed data through CURE GABA-A.

Your timelines. Your milestones. Your lived experience.

Publications like this shape clinical care worldwide.

Without them, rare diseases remain misunderstood.

Your voice is importantly. Your story is important and your data matters is important. This is why you share it!

Share your story: curegabaa.org/submit-your-story

Book a consult here: https://curegabaa.org/consultation/

Share your data in our digital natural history study here: CUREGABAA.acrossmatrix.com

Support the mission: curegabaa.org/donate

One Step Closer to CURE GABA-A

PatientLedScience EpilepsyResearch GABA GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRG1 GABRG2 GABRG3 GABRR1 GABRR2 GABRR3 GABRE GABRD GABRQ GABRP

CURE GABA-A | LP352 small-molecule clinical trial(not funded by CURE GABA-A)We wanted to share an update with our commun...
01/21/2026

CURE GABA-A | LP352 small-molecule clinical trial

(not funded by CURE GABA-A)

We wanted to share an update with our community after recently speaking with representatives from Lundbeck and information about LP352, an investigational drug currently being studied for developmental and epileptic encephalopathies (DEEs).

Lundbeck is planning a webinar to discuss this further. The date will be announced soon.

LP352 is a small-molecule therapy originally developed by Longboard Pharmaceuticals and is now being advanced by Lundbeck following their acquisition. It is being evaluated in a placebo-controlled clinical trial for DEEs, including conditions such as Lennox-Gastaut syndrome. While this study is not specific to GABAARs, it is broadly focused on DEEs.

We appreciated the opportunity to learn directly from the Lundbeck team about the science behind LP352 and how families can access accurate information.

We can also share that one member of our patient community has been using LP352 with promising results.

As always, we strongly encourage families to talk with their neurologist or medical care team before considering any clinical study or treatment option. Your doctor is the best resource to help you decide what may be appropriate for your loved one.

If you’d like to learn more about the study, you can search NCT06719141 on ClinicalTrials.gov, email [email protected], or call (855) 628-2977.

We’re grateful for open conversations like these and for Lundbeck’s continued support of our community, including their sponsorship of our 2025 European Conference in Lisbon.

More updates coming soon.

Europe: https://deepdeestudy.global/
USA: https://deepdeestudy.com/

CURE GABA-A | LP352 small-molecule clinical trial(not funded by CURE GABA-A)We wanted to share an update with our commun...
01/21/2026

CURE GABA-A | LP352 small-molecule clinical trial

(not funded by CURE GABA-A)

We wanted to share an update with our community after recently speaking with representatives from Lundbeck and information about LP352, an investigational drug currently being studied for developmental and epileptic encephalopathies (DEEs).

Lundbeck is planning a webinar to discuss this further. The date will be announced soon.

LP352 is a small-molecule therapy originally developed by Longboard Pharmaceuticals and is now being advanced by Lundbeck following their acquisition. It is being evaluated in a placebo-controlled clinical trial for DEEs, including conditions such as Lennox-Gastaut syndrome. While this study is not specific to GABAARs, it is broadly focused on DEEs.

We appreciated the opportunity to learn directly from the Lundbeck team about the science behind LP352 and how families can access accurate information.

We can also share that one member of our patient community has been using LP352 with promising results.

As always, we strongly encourage families to talk with their neurologist or medical care team before considering any clinical study or treatment option. Your doctor is the best resource to help you decide what may be appropriate for your loved one.

If you’d like to learn more about the study, you can search NCT06719141 on ClinicalTrials.gov, email [email protected], or call (855) 628-2977.

We’re grateful for open conversations like these and for Lundbeck’s continued support of our community, including their sponsorship of our 2025 European Conference in Lisbon.

More updates coming soon.

Europe: https://deepdeestudy.global/
USA: https://deepdeestudy.com/

CURE GABA-A | Running for Raina and CURE GABA-A Our amazing CURE GABA-A community member Brian () has been racing Ironma...
01/19/2026

CURE GABA-A | Running for Raina and CURE GABA-A

Our amazing CURE GABA-A community member Brian () has been racing Ironmans and marathons with one powerful purpose: raising awareness and funds to help bin awareness and funds to our community.

Right now, he’s entered in a contest for an Ironman Texas entry, and we need to rally behind him!

👉 Please search for , find his comment, LIKE it, and leave a supportive reply.

Your engagement truly matters and helps push his story to the top.

Brian runs every mile for families facing drug-resistant epilepsy in our community. His races help fuel the upcoming GRANN PHARMACEUTICALS mRNA projects we have in the pipeline and bring hope to children. He is out there pounding the pavement for ALL of us.

Let’s show him the strength of the CURE GABA-A community 💪

And if you’re a runner (or want to be!), please reach out to learn how you can join our growing running community and help turn your miles into impact.

Thank you for helping us lift up one incredible dad, advocate, and athlete who is fighting for our kids every step of the way!

Julia Frances

CURE GABA-A | Genetic Counseling Bill https://mstr.app/3c198882-3b4b-4cec-a007-9d935c4119ceHi! 👋 We wanted to let you kn...
01/13/2026

CURE GABA-A | Genetic Counseling Bill

https://mstr.app/3c198882-3b4b-4cec-a007-9d935c4119ce

Hi! 👋 We wanted to let you know that a bill supporting access to genetic counseling has been reintroduced in Congress.

Your voice matters. If you’re willing, please take a moment to send a message to lawmakers using this action alert link above.

Thank you for standing up for patients 💜

GABRA6 GABRB1 GABRB2 GABRB3 GABRG1 GABRG2 GABRG3 GABRR1 GABRR2 GABRR3 GABRE GABRD GABRQ GABRP

Address

30765 Pacific Coast Highway Suite 366
Malibu, CA
90265

Website

Alerts

Be the first to know and let us send you an email when Cure Gaba-A posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Organization

Send a message to Cure Gaba-A:

Shortcuts

Share

Category