American Journal of Physiology-Endocrinology and Metabolism

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American Journal of Physiology-Endocrinology and Metabolism

Published by the American Physiological Society, the journal features original, mechanistic studies o

The American Journal of Physiology - Endocrinology and Metabolism publishes original, mechanistic studies on the physiology of endocrine and metabolic systems. Physiological, cellular, and molecular studies in whole animals or humans will be considered. Specific themes include, but are not limited to, mechanisms of hormone and growth factor action; hormonal and nutritional regulation of metabolism, inflammation, microbiome and energy balance; integrative organ cross talk; paracrine and autocrine control of endocrine cells; function and activation of hormone receptors; endocrine or metabolic control of channels, transporters and membrane function; temporal analysis of hormone secretion and metabolism; and mathematical/kinetic modeling of metabolism. Novel molecular, immunological, or biophysical studies of hormone action are also welcome.

10/15/2026

Today's article is especially helpful for high-risk populations, Impact of the trans-ancestry polygenic risk score on type 2 risk, onset age and progression among population in Taiwan (Shi-Heng Wang et al.):

https://ow.ly/Awjm50ZY98T

10/13/2026

An equally large and talented team from University of New South Wales Sydney put together today's spotlight piece, Oocyte and cumulus cell cooperativity and metabolic plasticity under the direction of factors (Dulama Richani et al.):

https://ow.ly/L8QX50ZXkyZ

10/12/2026

Research Article by AR Quirk et al. Females with display evidence of and
https://ow.ly/Wnfy50ZVwEa

10/08/2026

You only need a moment to check out today's Short Report in Immunometabolism, Bruton’s tyrosine kinase (BTK) inhibitors alter blood and insulin in mice but reduce inflammation independent of (Darryl Chan et al. ):

https://ow.ly/tu4b50ZU4H3

10/07/2026

👉 This new Call for Papers explores the intricate interplay among the nervous, immune, endocrine and metabolic systems, revealing these networks as a dynamic regulatory system rather than isolated physiological domains. Learn more at https://ow.ly/TXJZ50ZUVtg.

10/06/2026

This afternoon take a moment to review today's APS select article, Time-restricted reveals a role for neural clocks in optimizing daily -metabolic coupling in mice (Aaron Jones et al. ):

https://ow.ly/teUJ50ZU4Bo

10/05/2026

Research Article by M Hirlemann et al. Additive effects of metformin on glucose homeostasis after metabolic-bariatric surgery in nonobese insulin-deficient diabetic rats
https://ow.ly/xJZS50ZR8ik

10/02/2026

Research Article by R Retnakaran et al. () -lowering in may be mediated by improved proinsulin processing without better β-cell compensation
https://ow.ly/2taV50ZR8f3

10/01/2026

From our Metabolism collection comes today's spotlight piece, The lactate oxidation complex: endpoint for carbohydrate carbon disposal (Robert Leija et al.):

https://ow.ly/wmra50ZTHPT

09/30/2026

Research Article by K Prins et al. () Enhanced behavioral responses to administration are unaffected by ghrelin deficiency in a DHT-induced mouse model
https://ow.ly/Xr8j50ZR8c7

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