06/04/2026
Rare diseases like DADA2 can cause life-threatening inflammation, strokes, bone marrow failure, and other serious complications — but researchers are working to better understand why patients experience the disease so differently.
With support from the Rheumatology Research Foundation’s Career Development Bridge Funding: R Bridge award, Dr. Lee’s research is uncovering key immune system pathways involved in DADA2 and helping pave the way for more personalized treatments in the future.
Findings from his research may impact patients by:
✨Helping doctors better predict how DADA2 will affect each patient, allowing earlier diagnosis, closer monitoring, and more personalized care.
✨ Leading to more targeted treatments by identifying the specific immune pathways involved in different forms of the disease.
✨ Building resources for future discoveries, including patient biobanks and laboratory models that may accelerate the development of new therapies for DADA2 and related inflammatory diseases.
Learn more about this research and its impact on the RheumLab. https://rheumlab.org/understanding-inflammation-in-a-rare-disease-called-dada2/