15/06/2026
Since the paper is now officially published, it is better to update the announcement from "accepted" to "published" and include the final DOI and article link. For LinkedIn and Facebook, a slightly more concise and impact-oriented version generally performs better.
đđą NEW PUBLICATION ALERT FROM THE NGS-4-ECOPROD CONSORTIUM! đąđ
We are proud to announce the publication of a new scientific article arising from WP1 â Task 1.2 (Extremozymes) of the Horizon Europe Twinning Project NGS-4-ECOPROD (Grant Agreement No. 101079425). đđ§Ź
đ Published in the International Journal of Molecular Sciences (IJMS, Q1)
đŹ Title:
Hybrid Whole-Genome Sequencing of Penicillium crustosum CTM10622 Uncovers a Highly Thermostable Alkaline Serine Lipase with Biotechnological Relevance
đ DOI:
https://doi.org/10.3390/ijms27125389
đ Full Article:
https://www.mdpi.com/1422-0067/27/12/5389
đ©âđŹđšâđŹ Authors:
Sondes Mechri, Afef Najjari, SĂ©verine Croze, Fakher Frikha, Nadia Zarai, Hadda-Imene Ouzari, Alexandre Noiriel, Ebru Toksoy Ăner, Abdelkarim Abousalham, Marilize Le Roes-Hill, Slim Tounsi, Joel Lachuer*, and Bassem Jaouadi*
đ Published in the Macromolecules Section of IJMS.
This study highlights the power of hybrid whole-genome sequencing combining Illumina and Oxford Nanopore technologies to explore extremophilic fungi isolated from Tunisian extreme environments. Through comprehensive genomic analysis, we identified and characterized a novel highly thermostable alkaline serine lipase exhibiting remarkable potential for industrial biotechnology applications, including green biocatalysis, biodiesel production, waste valorization, and detergent formulations.
đ This publication represents another major scientific milestone for the NGS-4-ECOPROD consortium and complements our previous achievements:
â
Whole-genome sequencing-guided discovery of a novel thermostable protease from Streptomyces cyaneofuscatus
(International Journal of Biological Macromolecules)
https://doi.org/10.1016/j.ijbiomac.2025.146696
â
Integrated metagenomic and metataxonomic exploration of Tunisian hypersaline ecosystems
(International Journal of Molecular Sciences)
https://www.mdpi.com/1422-0067/27/11/4714
Together, these studies demonstrate how genomics, metagenomics, and functional biotechnology can accelerate the discovery of novel extremozymes and eco-friendly biomolecules from underexplored extreme ecosystems.
đĄ Acknowledgment
This work was carried out within the framework of the European Unionâs Horizon Europe Research and Innovation Programme under HORIZON-WIDERA-2021-ACCESS-03-01 through the Twinning Project NGS-4-ECOPROD:
âFROM NEXT GENERATION SEQUENCING MICROORGANISMS TOWARDS ECOFRIENDLY BIOTECH BASED PRODUCTSâ
đ€ The project is coordinated by Prof. Slim Tounsi at the Centre of Biotechnology of Sfax (CBS, Tunisia), in partnership with UniversitĂ© Claude Bernard Lyon 1 (France) and Georg-August University of Göttingen (Germany), with strong scientific collaborations extending to South Africa and TĂŒrkiye.
đ We sincerely thank all researchers, students, collaborators, reviewers, and partner institutions whose dedication and teamwork made this achievement possible.
đ Advancing sustainable biotechnology through genomics, extremozymes, and international scientific excellence.
Centre de Biotechnologie de Sfax - Ù
۱ÙŰČ Ű§ÙŰšÙÙŰȘÙÙÙÙÙŰŹÙۧ ۚ۔ÙۧÙŰł