17/06/2026
Researchers at Mie University in Japan, led by Ryotaro Hashizume, used CRISPR-Cas9 gene-editing technology to remove the extra chromosome 21 responsible for Down syndrome in laboratory-grown human cells.
The team developed a technique called allele-specific editing, allowing them to target and eliminate the extra chromosome while leaving the normal chromosomes untouched.
After the extra chromosome was removed, the edited cells showed healthier function, faster growth, and lower levels of biological stress.
Scientists say the breakthrough targets the root genetic cause of Down syndrome, but the research has only been demonstrated in human cells and not in living patients.
Experts say the research remains far from clinical use but could mark a major step forward in genetic medicine.
