Exovent - Breathe Freely

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A charity supporting a collaboration of medics, engineers, scientists and technology specialists to develop novel breathing and ventilation support systems to help patients with respiratory illnesses . , , , The charity wishes to fund several varied designs so that this type of ventilation support can assist even the poorest of economies helping to protec

t the life of vulnerable children and adults throughout the World. Negative pressure ventilation ( ) is not a new concept and many people will remember the Iron Lungs that provided breathing assistance to Polio sufferers during the 1950’s epidemic. Our modern high-tech systems are smaller, lighter advanced designs, although they essentially use the same principle of helping a patient expand the chest (by reducing the pressure around the abdomen) which helps draw air into the lungs as though the patient was breathing naturally. Patients do not need to be put under anaesthetic or have a tube inserted into the mouth with exovent, they can remain awake and conscious allowing them to eat, drink and talk whilst receiving ventilatory support. 💙

Reg Charity Number: 1189967
Company Number: 12661070

19/08/2025

, our international pioneer groups and industry partners Portsmouth Aviation Limited believe in ‘sticking our neck out’ for the benefits of Negative Pressure Ventilation ( ); we want to make NPV a readily available option around the world for suffering from .

NPV has over 100 years of that are proven to help give to those in . 🧑‍⚕️

It was in 1928 that NPV became a true clinical reality with the development of the , it was the first reliable method of prolonged respiratory support and throughout most of the 19th century and the first half of the 20th century.

moved away from negative to positive pressure in the 1950s, largely because of a shortage of heavy and bulky iron lung devices and the development of smaller positive pressure devices. However, positive pressure was not physiologically superior.

Today, utilising aluminium and composite materials to make an ultra-lightweight torso-only device that weighs just 11Kg in comparison to the historical full-body chamber devices which weighed up to 300Kg. 🏋‍♀️ Both and evidence suggest that a modern device will provide an effective non-invasive ventilatory alternative to , with the additional possibility of preventing escalation of the patient to intubation with sedation and PPV.

Find out more about us at our website: www.exovent.org

To help sick lungs donate at: https://gofund.me/0471bad8

08/07/2025

When someone has their lungs aren’t working as well as they should be, generally this means they cannot get the correct amount of air into the , which means less oxygen (O2) gets into the blood [and less Carbon Dioxide (CO2) is removed from the lungs] and this can cause all sorts of problems, often becoming serious & life threatening.

As lung function weakens & try to assist patients by providing oxygen supplied through a , but if this doesn’t provide enough improvement the will consider full breathing support, this is known as .

Today, available systems generally blow air into the patient lungs to inflate them to get the required oxygen into (CO2 out of) the lungs and the bloodstream, this is known as Positive Pressure Ventilation.

To effectively blow the air in, a tube must be inserted through the mouth & into the throat; this is often uncomfortable and patients are normally asleep (given an anaesthetic) or heavily sedated throughout the time that mechanical ventilation is required.

Negative Pressure Ventilation ( ) is different. It works by reducing the air pressure (sucking a little air out) of the pod that is around the torso (from neck to hip), this very gently assists the chest muscles to expand helping to take air into the body using your natural breathing mechanism. So, with NPV a patient:

Can be .
Can more naturally without a tube into their mouth.
Can , and talk with loved ones & medical staff to make conscious care choices. 🍇 🥤 🧑‍⚕️

Exovent, our International Pioneer groups and our partners Portsmouth Aviation Limited think these aspects are worth ‘sticking our neck out’ to make NPV a readily available option for .

To help sick lungs donate at: https://gofund.me/0471bad8
Find out more about us at our website: www.exovent.org

18/03/2025

Positive Pressure Ventilation ( ), while life-saving in critical care settings, introduces several challenges and risks primarily due to its effects on pleural pressure (Ppleural). Unlike natural respiration, where Ppleural remains negative throughout the breathing cycle, PPV raises Ppleural, leading to several potential complications.

(IV) Clinical implications and protective strategies: the increased risk of VILI associated with PPV highlights the importance of strategies that minimize Ppleural. Such strategies include synchronization with patient efforts, prone positioning, and the careful use of PEEP and recruitment maneuvers. These approaches aim to limit the harmful effects of elevated Ppleural and improve patient outcomes.

For full details and further information on how Negative Pressure Ventilation ( ) may help avoid many of these adverse side effects, please see the recent publication ‘The role of pleural pressure in inducing and other adverse effects of positive pressure ventilation’ published in the Journal of Thoracic Disease. https://jtd.amegroups.org/article/view/93053/html

Our charitable vision: To have a world where those with have access to non-invasive breathing support when they need it.😎

To help sick lungs donate💰at: https://gofund.me/0471bad8

Find out more about us at our website: www.exovent.org

19/02/2025

Positive Pressure Ventilation ( ), while life-saving in critical care settings, introduces several challenges and risks primarily due to its effects on pleural pressure (Ppleural). Unlike natural respiration, where Ppleural remains negative throughout the breathing cycle, PPV raises Ppleural, leading to several potential complications.

(III) Impact on pleural fluid dynamics: the transition to positive Ppleural disrupts the delicate balance maintained by negative Ppleural and capillary forces, which normally keep a thin, lubricating layer of pleural fluid around the lungs. This disruption can reduce the effectiveness of the pleural fluid as a spacer and lubricant, increasing the likelihood of damage to the pleurae’s .

For full details and further information on how Negative Pressure Ventilation may help avoid many of these adverse side effects, please see the recent publication ‘The role of pleural pressure in inducing pneumothorax and other adverse effects of positive pressure ventilation’ published in the Journal of Thoracic Disease.
https://jtd.amegroups.org/article/view/93053/html

Our charitable vision: To have a world where those with have access to non-invasive breathing support when they need it.

To help sick lungs donate at: https://gofund.me/0471bad8

Find out more about us at our website: www.exovent.org

05/02/2025

Positive Pressure Ventilation ( ), while life-saving in critical care settings, introduces several challenges and risks primarily due to its effects on pleural pressure (Ppleural). Unlike natural respiration, where Ppleural remains negative throughout the breathing cycle, PPV raises Ppleural, leading to several potential complications.

(II) Airway closure and atelectasis: positive Ppleural can cause cyclic airway closure, particularly in dependent regions of the lung, contributing to . This airway closure not only impairs oxygenation but also sets the stage for subsequent lung injury, including the risk of pneumonia.

For full details and further information on how Negative Pressure Ventilation may help avoid many of these adverse side effects, please see the recent publication ‘The role of pleural pressure in inducing pneumothorax and other adverse effects of positive pressure ventilation’ published in the Journal of Thoracic Disease.
https://jtd.amegroups.org/article/view/93053/html

Our charitable vision: To have a world where those with a have access to non-invasive breathing support when they need it. 😎

To help sick lungs donate 💸 at: https://gofund.me/0471bad8

Find out more about us at our website: www.exovent.org

28/01/2025

Positive Pressure Ventilation ( ), while life-saving in critical care settings, introduces several challenges and risks primarily due to its effects on pleural pressure (Ppleural). Unlike natural , where Ppleural remains negative throughout the cycle, PPV raises Ppleural, leading to several potential complications.

(I) Ppleural and lung mechanics: the elevation in Ppleural caused by positive airway pressure leads to the being pushed against the wall, contrasting with the pulling away of the lung during natural, negative pressure respiration. This change increases friction between the pleurae, leading to shear stress and potential damage to lung parenchyma. 😎

For full details and further information on how Negative Pressure Ventilation may help avoid many of these adverse side effects, please see the recent publication ‘The role of pleural pressure in inducing pneumothorax and other adverse effects of positive pressure ventilation’ published in the Journal of Thoracic Disease. https://jtd.amegroups.org/article/view/93053/html 👏

Our charitable vision: To have a world where those with have access to non-invasive breathing support when they need it. 😎

To help sick lungs donate at: https://gofund.me/0471bad8 💵

Find out more about us at our website: www.exovent.org

21/10/2024

The Lit & Phil (Literary & Philosophical Society) was founded in 1793 and has been at home on Westgate Road in the centre of upon Tyne since 1825.

This beautiful, free to visit and browse library is only a few minutes from Central Station where it hosts an exciting and diverse range of events including , , , and ; it is also a wonderful space for , and .

https://www.litandphil.org.uk/

In 1879, at the Lit & Phil, Sir Joseph Wilson Swan, , and first demonstrated his incandescent light bulb and the nearby Mosley Street was the first street in the world to be lit by electric bulbs.

This Thursday (26 October) our esteemed exovent team are pleased to have the opportunity to talk at this venue about 'the science and physiology of breathing, and how to build a Negative Pressure Ventilator.'

Both and evidence suggest that a modern device will provide an effective non-invasive ventilatory alternative to , with the additional possibility of preventing escalation of the patient to intubation and PPV. 👩‍⚕️ 😎

So, if you are in the Newcastle vicinity please come along to this fabulous venue, listen to our colleagues, and perhaps we hope, have a lightbulb moment regarding the future of ventilation…

Find out more about us at our website: www.exovent.org

To help sick lungs donate at: https://gofund.me/0471bad8

30/09/2024

Ex-ovent marks the spot!

Are you travelling to ExCel London for the Anaesthesia & Critical Care conference this week? 😎

If so, this map might help you to find the forgotten treasure that is Negative Pressure Ventilation ( ). Although, it might be easier to simply follow the signs to 'Stand G63' where you will be able to meet with our partners 42 Technology and Portsmouth Aviation Limited; please come along for a chat about the future of technology and innovation, and to see the exovent NPV system in action.

Also, ‘Hear from the Experts’ 📣 on Wednesday 2 October 12.15 in Clinical Theatre D: https://lnkd.in/egQhXayq

, ARDS

24/09/2024

Dr. Diane Downie was a for over 30 years and is an Expert Member of the Research Ethics Committee.

Diane joined Exovent just before the first UK lockdown and her input has been immeasurable across numerous aspects, from research & design to assisting our Pioneer Groups with overseas exovent development in , and to providing education & training for others working with us. 🫶

If you are heading to the next week please come along and listen to her talk about Negative Pressure Ventilation ( ). Or alternatively pop along to stand G63 to see the exovent system and meet with our partners 42 Technology and Portsmouth Aviation Limited to discuss the exciting NPV innovation. 😎

,

02/07/2024

We recently attended the Intensive Care Society in and had many interesting conversations with attendees who wanted to find out more about the future of Negative Pressure Ventilation ( ) and the no-Iron Lung. 🚫

Our industry partners Portsmouth Aviation Limited are utilising aluminium and composite materials to make an ultra-lightweight torso-only device which weighs 11Kg in comparison to the historical full-body chamber devices which weighed up to 300Kg. 🏋‍♂️

Negative Pressure Ventilation became a true clinical reality in 1928 with the development of the , which was initially designed and built by an , Phillip Drinker, a Charles McKhann, and Louis Shaw, a . It was the first reliable method of prolonged respiratory support and throughout most of the 19th century and the first half of the 20th century.

Both and evidence suggest that a modern device will provide an effective non-invasive ventilatory alternative to , with the additional possibility of preventing escalation of the patient to intubation and PPV. 👩‍⚕️ 😎

Find out more about us at our website: www.exovent.org

To help sick lungs donate at: https://gofund.me/0471bad8

18/06/2024

We’ve had a brilliant day at the Intensive Care Society congress in today. 👏

Special thanks to Professor Hugh Montgomery who took time to stop by and meet with our Chairman (Professor David Howard) to facilitate some great thinking ‘outside the box’, whilst around the box (exovent chamber). 😁

Huge thanks to all those who took the time to visit us with very open minds and great questions about Negative Pressure Ventilation ( ) too. 😎

If you're attending the this week please come visit us tomorrow and Thursday, we look forward to meeting you. 🤝

Both and evidence suggest that a modern NPV device with an ultra-lightweight torso-only cabinet covering only the chest and abdomen will provide an effective non-invasive ventilatory alternative to , with the additional possibility of preventing escalation of the patient to intubation and PPV.

Exovent is a that supports international industry partners such as Portsmouth Aviation Limited to develop Negative Pressure devices by utilising with over 100 years of that are proven to help give to those in .

Find out more about us at our website: www.exovent.org

To help sick lungs donate at: https://gofund.me/0471bad8

08/06/2024

Are you heading to this month for the Intensive Care Society SOA24 congress?

'Twenty two years after its inception, the Intensive Care Society’s, State of the Art Congress (SOA) continues to unite intensive care professionals from across the UK and the globe.'

Exovent are very pleased & proud to be in attendance and you will find some of our team (including our Chairman, Professor David Howard) manning our exhibition stand; so if you have a little time please come by and find out how with over 100 years of history is a technology featuring within the Innovation Zone!

We look forward to meeting you and hearing any questions, comments and thoughts you have about both here in the UK, and from around the World.

Find out more about at: https://ics.ac.uk/soa.html

Our charitable vision: To have a world where those with a have access to non-invasive breathing support when they need it. 👨‍⚕️👩‍⚕️

To help sick lungs around the World donate at: https://gofund.me/0471bad8

Find out more about us at our website: www.exovent.org

Address

10 Queen St Place
London
EC4R1BE

Website

https://www.exovent.org/

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