20/10/2026
Alzheimer's disease is the most common form of dementia, but it is not the only one.
NeuRA's Associate Professor Emma Devenney explained to ABC Canberra that dementia is a broad term for progressive, neurodegenerative changes in the brain. "If you have this combination of abnormal pathologies in your brain, then that's how we deem it to be Alzheimer's disease," she says.
Much of what we know about how dementias present comes from people who generously donated their brains after death, such as to the Sydney Brain Bank at NeuRA, allowing researchers to link what happens in the brain with what people experienced in life.
Diagnosis is also changing. Traditionally, a diagnosis relied on memory tests and brain scans, which are around expensive and invasive. Using blood-based biomarkers to measure the proteins amyloid and tau offers a method of diagnosis with far greater accessibility and equity - one of the drivers behind NeuRA's launch of the Asia Pacific Centre of Excellence for Alzheimer's Disease Diagnosis.
As Associate Professor Devenney told the ABC, "Blood-based biomarkers are just like going to your GP or pathology centre and having a blood test, which you would have for thyroid or iron."
This makes earlier diagnosis far more accessible. "Knowledge is power, and I'm finding more and more people want to know and they want to have that earlier diagnosis," she said, adding that "the earlier we treat, the better."